Immunization Adjuvants
Immunization Adjuvants
MilliporeSigma™ Calbiochem™ Freund's Incomplete Adjuvant, Modified
Yellow oily heat sterilized liquid
BD Difco™ Adjuvants
Used to prepare antigen-adjuvant emulsions. BD™ Difco™ Adjuvants are used in immunological studies with laboratory animals. (Not intended for human or therapeutic use.)
MP Biomedicals™ Freund's Adjuvant, Complete
Enhances the antibody response of animals injected with antigen. Made by a modification of Freund's technique
Thermo Scientific™ Imject™ Freund's Complete Adjuvant (FCA)
Stimulate a nonspecific immune response using complete (CFA) or incomplete (IFA) formulations of the popular Freund's adjuvant; offered in 10mL ampules.
MilliporeSigma™ Calbiochem™ Freund's Complete Adjuvant, Modified, Mycobacterium butyricum
Clear amber to slightly cloudy bacterial suspension
MP Biomedicals™ Freund's Incomplete Adjuvant
Used with subsequent boosts to increase antibody titer following initial animal injection with Freund's Complete Adjuvant
MP Biomedicals™ Freund's Adjuvant, Incomplete
a mixture containing mineral oil and Arlacel
Promotions are available
Thermo Scientific™ Imject™ Freund's Incomplete Adjuvant (FIA)
Stimulate a nonspecific immune response using complete (CFA) or incomplete (IFA) formulations of the popular Freund's adjuvant; offered in 10mL ampules.
Invivogen POLY(I:C) (HMW) VACCIGRADE
Poly(I:C) is a synthetic double-stranded RNA, that can activate the immune response through two distinct PRRs. Endosomal poly(I:C) activates TLR3 while cytosolic poly(I:C) activates RIG-I/MDA-5. Triggering the TLR3 pathway induces IL-12 and type I IFNs production, while stimulation of MDA-5 enhances the production of type I IFNs. Poly(I:C) promotes Th1 biased immunity through its induction of IL-12 and type I IFNs.
Invivogen ALUMINUM HYDROXIDE GEL 250ML
Alhydrogel adjuvant 2% is an aluminium hydroxide (referred to as alum) wet gel suspension. Alum acts primarily through the formation of a depot at the injection site, enabling enhanced antigen availability, activation of antigen presenting cells (APCs) and uptake by immune cells. It can also activate innate immunity pathways triggered by pattern recognition receptors (PRRs). The NLR pathway has been recently described as an important mechanism in alum adjuvancy. Alum has been shown to activate the NLRP3 inflammasome although its role in alum-induced antibody response is controversial. 21645-51-2.
Invivogen MPLA Synthetic VacciGrade, 1 mg
MPLA is a low-toxicity derivative of lipopolysaccharide (LPS), that retains the immunologically active lipid A portion of the parent molecule. While the toxicity associated with LPS prohibits its potential clinical use, MPLA is being developed as a vaccine adjuvant. Both LPS and MPLA are TLR4 agonists, but they signal through different adaptors, MyD88 and TRIF, respectively. The reduced toxicity of MPLA is attributed to the preferential recruitment of TRIF upon TLR4 activation, resulting in decreased induction of inflammatory cytokines.
Invivogen AddaVax™, Squalene-oil-in-water, 10mL
Specificity: Th1/Th2 response. Working concentration: 1:1 (AddaVax™:antigen). Quality control: Sterility guaranteed, Endotoxin level < 1 EU/ml, Particle size ~ 160 nm. AddaVax™ is a squalene-based oil-in-water nano-emulsion.
Invivogen IFA, 10 mL
IFA (Incomplete Freund’s adjuvant) is one of the most commonly used adjuvants in research. It is prepared from non-metabolizable oils. IFA can be used to produce water-in-oil emulsions of antigens. IFA induces a predominantly Th2-biased response through the formation of a depot at the injection site and the stimulation of antibody producing plasma cells.
Invivogen CL429 VACCIGRADE 5MG
CL429 VacciGrade; 5mg; TLR2 & NOD2-based adjuvant; sterile white lyophilized powder.
Invivogen AS03-like Adjuvant, 10 mL
AddaS03 is an oil-in-water nano-emulsion adjuvant, with a formulation highly similar to that of the adjuvant system AS03, a fundamental component of influenza vaccines. It is composed of the same percentage of two biodegradable oils, squalene and DL-alpha-tocopherol, and the surfactant, polysorbate 80 (Tween 80), for increased stability.
Invivogen Adju-Phos adjuvant, 250 mL
Adju-Phos adjuvant is an aluminium phosphate wet gel suspension. It induces a Th2 response by improving the attraction and uptake of antigen by antigen-presenting cells (APCs). It can also activate innate immunity pathways triggered by pattern recognition receptors (PRRs).
Invivogen ALUMINIUM HYDROXIDENLRP3 500UL
Aluminium hydroxide; NLRP3 inflammasome inducerCat # TLRL-ALOH
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