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5-Azacytidine is an analog of the nucleoside cytidine which can be incorporated into DNA and RNA. 5-Azacytidine acts as an epigenetic modifier by incorporating into DNA where it irreversibly binds to DNA methyltransferases, thus inhibiting their activity. REPROGRAMMING· Increases reprogramming efficiency of mouse fibroblasts to induced pluripotent stem (iPS) cells by inducing full reprogramming of partially reprogrammed cells (Mikkelsen et al.).· Resets epigenetic memory in mouse iPS cells, in combination with Trichostatin A (Kim et al.). DIFFERENTIATION· Enhances differentiation to cardiomyocytes from human embryonic stem cells (Yoon et al.).CANCER RESEARCH· Wide range of anti-metabolic activities when tested against cultured cancer cells and an effective chemotherapeutic agent for acute myelogenous leukemia
50-114-3043 EDU 5-ETHYNYL-2-DEOXYUR 250
50-114-3044 EDU 5-ETHYNYL-2-DEOXYUR 500
Medchemexpress, HY-13637 5g Ganciclovir BW 759;2'-Nor-2'-deoxyguanosine CAS:82410-32-0 Formula:C9H13N5O4 IC50: 5.2 μM (FHV-1) Purity:98% Ganciclovir is a potent inhibitor of viruses of the herpes family, including cytomegalovirus ( CMV ), with an IC 50 of 5.2 μM for feline herpesvirus type-1 (FHV-1). Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress, HY-17026 1g Gemcitabine NSC 613327;LY188011 CAS:95058-81-4 Formula:C9H11F2N3O4 DNA synthesis Purity:98% Gemcitabine is a DNA synthesis inhibitor with IC 50 of 37.6, 42.9, 92.7, 89.3 and 131.4 nM in BxPC-3, Mia Paca-2, PANC-1, PL-45 and AsPC-1 cells, respectively. Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress, HY-B0003 1g Gemcitabine (Hydrochloride) LY 188011 hydrochloride CAS:122111-03-9 Formula:C9H12ClF2N3O4 DNA synthesis Purity:98% Gemcitabine hydrochloride is a DNA synthesis inhibitor with IC 50 of 37.6, 42.9, 92.7, 89.3 and 131.4 nM in BxPC-3, Mia Paca-2, PANC-1, PL-45 and AsPC-1 cells, respectively. Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress, HY-13599 100mg Cladribine 2-Chloro-2′-deoxyadenosine;CldAdo;2CdA CAS:4291-63-8 Formula:C10H12ClN5O3 Purity:98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress, HY-13465 5mg VCH-916 CAS:1200133-34-1 Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.