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Ambeed | 2-Hydroxy-2-phenylacetic acid | 25g | 552661738 | A228156 | | 90-64-2 | MFCD00064250 | 152.149 | C8H8O3
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AM966 is a selective, potent and orally bioavailable antagonist of lysophosphatidic acid type 1 receptor (LPA1) with IC50 values of 17 and 19 nM for human or mouse LPA1, respectively [1]. Relative to LPA2, 3, 4, 5 receptors, AM966 shows 10-fold and 100-fold more selective in mouse and human cell lines for LPA1, respectively [1].In vitro, AM966 shows to inhibit LPA-induced chemotaxis in IMR-90 human lung fibroblasts, A2058 human melanoma cells and CHO cells expressing LPA1 receptors [1].In vivo, AM966 has been demonstrated to reduce total BALF cells, LDH activity, BALF collagen and total TGFβ concentrations in bleomycin-induced mice. Moreover, AM966 has been reported to block lung fibrosis, reduce lung inflammation and maintain body weight in mice induced by bleomycin [1]. Other sizes are also available. Please inqury us for quote.
Medchemexpress, HY-100882 5mg ONO-7300243 CAS:638132-34-0 ONO-7300243 is a novel, potent lysophosphatidic acid receptor 1 ( LPA1 ) antagonist with IC 50 of 0.16 μM. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Combi-Blocks | 3-(Methanesulfonylamino)benzonitrile | 1g | 232338032 | ST-9169 | 98.000 | 50790-30-2 | MFCD00116199 | 196.220 | C8H8N2O2S
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50-187-2145 GW3965 HYDROCHLORIDE 5MG
Medchemexpress, HY-111498A 10mg RGX-104 (free Acid) CAS:610318-54-2 RGX-104 free Acid is an orally bioavailable and potent liver-X nuclear hormone receptor (LXR) agonist that modulates innate immunity via transcriptional activation of the ApoE gene. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress, HY-17613 5mg Evocalcet CAS:870964-67-3 Evocalcet has an activating effect on calcium sensing receptor (CaSR) extracted from patent WO 2017061621 A1, compound A. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Evocalcet (KHK7580) is an novel oral calcimimetic agent which acts via allosteric activation of the calcium sensing receptor (CaSR). Evocalcet (0, 20 and 60 nM) dose-dependently increases cytoplasmic [Ca2+] concentrations with an EC50 value of 92.7 nM in hCaR-HEK293 cells.
Diclofenac 5g
Medchem Express / ONO-7300243 / 5mg / 446256258 / HY-100882 / / 638132-34-0 / MFCD30534399 / 461.558 / C28H31NO5
Diclofenac Sodium is a non-selective COX inhibitor with IC50 of 60 and 220 nM for ovine COX-1 and -2, respectively.Diclofenac is a non-steroidal anti-inflammatory agent (NSAID) with antipyretic and analgesic actions. Diclofenac sodium (Dc), an anti-inflam. Other sizes are also available. Please inqury us for quote.
Combi-Blocks | Diclofenac methyl ester | 1g | 232339317 | YC-0596 | 97.000 | 15307-78-5 | MFCD08273811 | 310.170 | C15H13Cl2NO2
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Combi-Blocks | 3-(Methanesulfonylamino)phenylacetic acid | 1g | 232337918 | ST-8757 | 95.000 | 407640-21-5 | MFCD03411194 | 229.250 | C9H11NO4S
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Medchem Express / TES-1025 / 5mg / 446259959 / HY-111365 / / 1883602-21-8 / [null] / 383.440 / C18H13N3O3S2
Medchem Express / RGX-104 (hydrochloride) / 2mg / 437899137 / HY-111498 / / 610318-03-1 / [null] / 632.550 / C34H34Cl2F3NO3