Your New Research Partner

Let Thermo Fisher Scientific be your partner in pharmacogenomics (PGx) research. We offer a variety of cost-effective options to assist you in developing tests to analyze genetic mutations involved in pharmacogenomics responses to medication.

We provide both low- and high-throughput systems that can be customized to meet your specific pharmacogenomics research needs.

Our two main solutions cover both next-generation sequencing (NGS) and real-time PCR technologies — depending on your needs.

  • If you wish to investigate fewer than 120 targets, our real-time PCR solution has been used by hundreds of laboratories around the world
  • If you are looking at a large number of genetic markers (120+), our next-generation sequencing approach may be optimal for you

Both platforms provide unlimited potential. Empower your pharmacogenomics research with the Applied Biosystems™ QuantStudio™ 12K Flex Real-Time PCR and Ion Next-Generation Sequencing Systems.

Applied Biosystems Qualified Solution for Pharmacogenomics

In Pharmacogenomics, There’s No Time to Waste

Applied Biosystems™ TaqMan® Assays combined with the Applied Biosystems QuantStudio 12K Flex Real-Time PCR System and Applied Biosystems™ OpenArray™ technology enable screening that is highly flexible and offers big cost savings and high throughput — all with a very simple workflow.

Easy Implementation

Both platforms offer a complete, integrated solution from sample to results with optimized protocols to get your lab quickly up to speed. Get started right away with an off-the-shelf panel.

For focused and fast pharmacogenomics results, you can use our off-the-shelf panels, which consist of the most common targets for PGx research applications. You can also choose your own content through our flexible content panels — selecting from our collection of redesigned TaqMan Assays — 2,700 TaqMan DME assays and millions of TaqMan copy number assays.

Next-Generation Sequencing Using the Ion S5 or Ion PGM Systems

In pharmacogenomics, individualized information is key. Expand your confidence in data results by running larger panels that broaden markers within your current gene set or extend markers to new genes providing a more expansive pharmacogenomics profile with the Ion Torrent™ Ion PGM™, S5™ or S5™ XL Systems, and Ion AmpliSeq™ Pharmacogenomics Research Panel.

Both platforms offer a complete, integrated solution from sample to results with optimized protocols to get your lab quickly up to speed.

Flexibility – It’s Your Choice

You can select either a pre-designed panel from our collection, or for maximum flexibility, design a custom panel with TaqMan Assays or Ion AmpliSeq Designer. The choice is yours.

Experimental Workflows

Use the simple workflows developed by Thermo Fisher Scientific to help evaluate changes to drug metabolism enzyme genes, including CYP2D6. Depending on your target markers and throughput goals, you may be able to make your assessments in less than 24 hours.

Workflow - Quantitative PCR solution using TaqMan Assays and QuantStudio 12K Flex System

Quantitative PCR Solution Using TaqMan Assays and the QuantStudio 12K Flex System

DME, SNP, and Indel Analysis

Choose from pre-defined Applied Biosystems TaqMan PGx panels or design your own using our 2,700 Applied Biosystems TaqMan DME Assays plus — custom TaqMan Assays.

Copy Number Variant Analysis

Analyze copy number variants (including CYP2D6) using the Applied Biosystems QuantStudio 12K Flex system for the flexibility needed to adjust your throughput from one to hundreds of samples per day.


NGS Solution Using Ion AmpliSeq Pharmacogenomics Research Panel and Ion PGM System

For Research Use Only. Not for use in diagnostic procedures.