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CAS: 78860-34-1 Molecular Formula: C32H30N2O4 Molecular Weight (g/mol): 506.602 InChI Key: XMGNJVXBPZAETK-UHFFFAOYSA-N Synonym: demethylasterriquinone b1,dmaq-b1,daq b1,2,5-dihydroxy-3-7-3-methyl-but-2-enyl-1h-indol-3-yl-6-2-1,1-dimethyl-allyl-1h-indol-3-yl-1,4 benzoquinone,2-2-1,1-dimethylallyl-1h-indol-3-yl-3,6-dihydroxy-5-7-3-methylbut-2-enyl-1h-indol-3-yl 1,4 benzoquinone,tocris-1819,2,5-cyclohexadiene-1,4-dione, 2-2-1,1-dimethyl-2-propenyl-1h-indol-3-yl-3,6-dihydroxy-5-7-3-methyl-2-butenyl-1h-indol-3-yl,2,5-cyclohexadiene-1,4-dione,2-2-1,1-dimethyl-2-propen-1-yl-1h-indol-3-yl-3,6-dihydroxy-5-7-3-methyl-2-buten-1-yl-1h-indol-3-yl,2,5-dihydroxy-3-2-2-methylbut-3-en-2-yl-1h-indol-3-yl-6-7-3-methylbut-2-enyl-1h-indol-3-yl cyclohexa-2,5-diene-1,4-dione,2,5-dihydroxy-3-7-3-methylbut-2-en-1-yl-1h-indol-3-yl-6-2-2-methylbut-3-en-2-yl-1h-indol-3-yl cyclohexa-2,5-diene-1,4-dione PubChem CID: 3013166 IUPAC Name: 2,5-dihydroxy-3-[2-(2-methylbut-3-en-2-yl)-1H-indol-3-yl]-6-[7-(3-methylbut-2-enyl)-1H-indol-3-yl]cyclohexa-2,5-diene-1,4-dione SMILES: CC(=CCC1=CC=CC2=C1NC=C2C3=C(C(=O)C(=C(C3=O)O)C4=C(NC5=CC=CC=C54)C(C)(C)C=C)O)C
PubChem CID | 3013166 |
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CAS | 78860-34-1 |
Molecular Weight (g/mol) | 506.602 |
SMILES | CC(=CCC1=CC=CC2=C1NC=C2C3=C(C(=O)C(=C(C3=O)O)C4=C(NC5=CC=CC=C54)C(C)(C)C=C)O)C |
Synonym | demethylasterriquinone b1,dmaq-b1,daq b1,2,5-dihydroxy-3-7-3-methyl-but-2-enyl-1h-indol-3-yl-6-2-1,1-dimethyl-allyl-1h-indol-3-yl-1,4 benzoquinone,2-2-1,1-dimethylallyl-1h-indol-3-yl-3,6-dihydroxy-5-7-3-methylbut-2-enyl-1h-indol-3-yl 1,4 benzoquinone,tocris-1819,2,5-cyclohexadiene-1,4-dione, 2-2-1,1-dimethyl-2-propenyl-1h-indol-3-yl-3,6-dihydroxy-5-7-3-methyl-2-butenyl-1h-indol-3-yl,2,5-cyclohexadiene-1,4-dione,2-2-1,1-dimethyl-2-propen-1-yl-1h-indol-3-yl-3,6-dihydroxy-5-7-3-methyl-2-buten-1-yl-1h-indol-3-yl,2,5-dihydroxy-3-2-2-methylbut-3-en-2-yl-1h-indol-3-yl-6-7-3-methylbut-2-enyl-1h-indol-3-yl cyclohexa-2,5-diene-1,4-dione,2,5-dihydroxy-3-7-3-methylbut-2-en-1-yl-1h-indol-3-yl-6-2-2-methylbut-3-en-2-yl-1h-indol-3-yl cyclohexa-2,5-diene-1,4-dione |
IUPAC Name | 2,5-dihydroxy-3-[2-(2-methylbut-3-en-2-yl)-1H-indol-3-yl]-6-[7-(3-methylbut-2-enyl)-1H-indol-3-yl]cyclohexa-2,5-diene-1,4-dione |
InChI Key | XMGNJVXBPZAETK-UHFFFAOYSA-N |
Molecular Formula | C32H30N2O4 |
CAS | 6089-09-4 |
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MDL Number | MFCD00004407 |
AG-879, a member of the tyrphostin family of tyrosine kinase inhibitors, inhibits NGF receptor (pp140c-trk) autophosphorylation selectively with no inhibition of EGF or PDGF receptor phosphorylation (IC50=10 µM). AG-879 inhibits NGF-induced neurite outgrowth in PC12 cells. Purity: ≥99% (HPLC). Solubility: Soluble in 100% ethanol (25mg/ml) or DMSO (25mg/ml). Long Term Storage: -20°C.
AG-879, a member of the tyrphostin family of tyrosine kinase inhibitors, inhibits NGF receptor (pp140c-trk) autophosphorylation selectively with no inhibition of EGF or PDGF receptor phosphorylation (IC50=10 µM). AG-879 inhibits NGF-induced neurite outgrowth in PC12 cells. Purity: ≥99% (HPLC). Solubility: Soluble in 100% ethanol (25mg/ml) or DMSO (25mg/ml). Long Term Storage: -20°C.