Pharma and Chemical
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Pharma and Chemical

BUCHI chemistry workflow solutions support many steps of your research, development, and production process. BUCHI is known to offer reliable, accurate, and easy-to-use equipment and instruments. Dependable equipment for evaporation, separation and purification, and freeze drying is critical for efficient synthesis and production. Accurate and automated melting point instruments help you analyze your samples and materials.

Complementary equipment used in the chemistry workflow allows for one supplier to support your technical and application needs: evaporate solvents from synthetic reactions, liquid extractions, filtrations, and preparative chromatography fractions; separate and purify complex reaction mixtures or extracts using flash or preparative HPLC; and use lyophilization to gently dry aqueous extractions or chromatography fractions.

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From evaporation to purification to drying and final analysis, BUCHI offers the equipment and instruments you need for reproducible chemistry research.

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Evaporation and Concentration

In 1957, BUCHI introduced the first commercial rotary evaporator. With technological expertise and user focus, it developed the Rotavapor into an intelligent and fully integrated system. BUCHI’s carefully conceived solutions meet various needs, whether you operate in research, development, or production. Its benchtop and industrial rotary evaporators and systems come with your choice of condensers, vacuum pumps, controllers, chillers, and other options to help you customize your solvent removal needs.

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Separation and Purification

Whatever the complexity or scale of your purification process, BUCHI’s preparative chromatography systems are designed to fulfill your changing needs. Pure Chromatography Systems offer prep HPLC and flash chromatography separations and purifications in a single, compact platform. Ensure your desired compounds are collected with a broad UV-Vis scanning range and industry-leading ELS detection for non-absorbing compounds or UV-active solvents. Together with a broad range of high-performance flash chromatography and prep HPLC columns, you get an optimized solution suited to your purification workflow.

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Freeze Drying

BUCHI has been producing user-friendly and highly beneficial solutions in laboratory evaporation for more than 55 years. Those decades of experience and quality demands feed directly into innovative solutions for freeze drying. For the first time, continuous freeze drying is available to a broad spectrum of applications from research and development to quality control, enabling you to efficiently dry aqueous extracts, chromatography samples, and peptides and proteins, or remove minute quantities of water from chemical samples. Freeze dried samples are stable for storage or testing when processed using one of BUCHI’s powerful freeze dryers.

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Analysis

With solutions to determine your melting and boiling points, BUCHI provides high-accuracy, automatic and/or visual determination and optional qualification packages to meet the highest regulatory standards. Automatic determination enables unattended analysis and provides results in video and data formats for review. An optimized heating block allows for faster cooling times and higher throughput. Fail-safe menu-guided calibration and verification with supplied standards and automated determination ensures accuracy and repeatability.

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Food and Beverage
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Food and Beverage

R&D is fundamental to any food and beverage processor's business. Developing new and improved products, meeting dynamic market demands, and getting to market quickly are keys to success. BUCHI sample preparation and purification products are designed to make your R&D role more efficient, productive, and automated.

Food and beverage R&D workflows require various steps of solvent and water removal, purification of natural or synthetic mixtures, and the isolation of target products. Final analysis is a critical step that depends on proper sample preparation and handling. Explore a range of BUCHI solutions to meet your workflow needs for intermediate and final product sample preparation.

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Purify complex mixtures, isolate compounds of interest, and prepare samples for analysis or storage.

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Separation and Purification

Whatever the complexity or scale of your purification process, BUCHI preparative chromatography systems are designed to fulfill your changing needs. BUCHI Pure Chromatography Systems offer prep HPLC and flash chromatography separations and purifications in a single, compact platform. Desired compounds are collected with a broad UV-Vis scanning range and industry-leading ELS detection for non-absorbing compounds or UV-active solvents. Together with high-performance flash chromatography and prep HPLC columns, you get an optimized solution suited to your purification workflow.

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Evaporation and Drying

BUCHI SyncorePlus instruments stand apart from the rest in parallel evaporation. Advanced automation features increase productivity, and its advanced design protects the desired analyte. Along with increased analyte recovery, solvent recovery of >95% is achieved without the consumption of nitrogen. Automated evaporation with analytical precision and safety of up to 96 samples to dryness, or concentration of up to 12 samples to residual volumes, increases throughput and allows you to proceed with other tasks.

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Freeze Drying

Freeze drying is a gentle form of drying and may be used to preserve foods without changing their appearance or taste. The process also avoids the loss and degradation of volatile compounds and results in a stable product with increased shelf life. As the market leader in laboratory evaporation, BUCHI offers the first laboratory freeze dryer with continuous sublimation and quick-design programming and running of methods. Infinite-Technology™ utilizes two alternately working condensers for continued operation.

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Environmental
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Environmental

A clean and safe environment is a prerequisite for health and quality of life. BUCHI contributes to improving the environment by providing market-leading solutions for sample preparation and solvent recovery to a wide range of industrial companies, environmental testing labs, consultants, and government authorities.

Samples from air, soil, sediment, sludge, waste, and wastewater are challenging to analyze. BUCHI offers solutions designed for quick, efficient, and reliable sample preparation for the assessment of environmental pollution. Compliance is also key, and these products will help you meet EPA, AOAC, ISO, and other regulatory methods.

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Automate sample preparation and solvent recycling with >95% solvent recovery and high analyte recovery.

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Solvent Recycling

BUCHI offers tools for efficient and ecological solvent recycling. From the lab-size BUCHI Rotavapor™ Evaporator for volumes up to three liters to an EX-proof version for volumes up to 30 liters, a range of capacities are available. The BUCHI Rotavapor R-220 Pro offers an economical option. With its 20-liter evaporating flask, it distills up to 19 liters of Acetone or 38 liters of Hexane within an hour. The integrated vacuum controller and the PTFE membrane pump complete the space-saving design. Plus, using BUCHI Rotavapor products for solvent recycling allows you to carry out other applications, too, including concentrations, extractions, and drying.

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Parallel Concentration

BUCHI SyncorePlus instruments stand apart from the rest in parallel concentration. Advanced automation features increase productivity, and its advanced design protects the desired analyte. Along with increased analyte recovery, solvent recovery of >95% is achieved without the consumption of nitrogen. Automated evaporation with analytical precision and safety of up to 96 samples to dryness, or concentration of up to 12 samples to residual volumes, increases throughput and allows you to proceed with other tasks.

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Freeze Drying

Sample preparation before extraction and analysis is key to achieving reproducible and accurate results. Residual water can impede extraction and lingering solvents can affect analytical outcomes. BUCHI Lyovapor™ freeze drying products can dry multiple samples at a time using a standard manifold, or several shelves of vials with a stoppering top. Samples can be monitored for endpoint determination to help ensure they are protected if sample temperatures rise. Freeze dried samples are stable for processing, testing, or storage when processed using BUCHI freeze dryers.

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Cannabis
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Cannabis

The safe investigation, production, and quality control of the active compounds in cannabis require a diverse portfolio of scientific equipment and instruments and related application knowledge. Growers, extractors, and final product manufacturers find that BUCHI’s portfolio offers many trusted solutions to support their workflows.

BUCHI’s solutions span the process workflow from evaporation and concentration after extraction to the purification of desired cannabinoids and final analysis of end products. BUCHI’s extended experience in the industry provides reliable equipment and support to the cannabis market.

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BUCHI’s comprehensive range of equipment is backed by experience and support that will take you from extraction to final product.

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Extraction and Concentration

Isolation of cannabinoids and therapeutic terpenoids typically requires the use of organic solvents for extraction or steps afterward. Industrial-scale rotary evaporators are commonly used to cover almost the entire range of solvent handling in cannabis production. Removal of the solvent is performed with careful vacuum and temperature control optimized to limit any degradation of the target cannabinoid compounds.

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Cannabinoid Separation

Flash chromatography is a suitable method for the separation of different compounds of cannabis extract from each other. With this technique, it is possible to produce pure cannabinoids like CBD or THC. Flash chromatography can also be used to remove unwanted substances, such as pesticides, from the extract. The resulting products are then concentrated again using a rotary evaporator.

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