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Tocris Bioscience™ SP 141

Name: Tocris Bioscience&trade; SP 141
Brand: Tocris Bioscience&trade;
SKU: 53-321-0
Price: 299.28 USD

High affinity MDM2 inhibitor

Supplier: Tocris Bioscience™ 5332/10

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Catalog No. 53-321-0

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Description

SP 141 is a high affinity MDM2 inhibitor (Ki = 28 nM); directly binds MDM2. SP 141 inhibits MDM2 expression and induces MDM2 autoubiquitination and proteasomal degradation. SP 141 attenuates growth of breast cancer xenograft tumors. SP 141 impairs liposarcoma growth in vitro and in human xenograft models. SP 141 is cell permeable.

Specifications

Purity	>98%
Molecular Weight (g/mol)	324.38
Quantity	10 mg

Description	SP 141
Product Type	SP 141

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Tocris Bioscience™ SP 141

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