Dextran Sulfate Sodium Salt, Colitis Grade (36,000 to 50,000), MP Biomedicals™

Induces severe colitis (inflammatory bowel disease) in laboratory animals

Catalog Number	Mfr. No.	Quantity
MP216011001	MP Biomedicals, Inc 0216011001	1 g
ICN16011010	MP Biomedicals, Inc 0216011010	10 g
MP216011025	MP Biomedicals, Inc 0216011025	25 g
ICN16011050	MP Biomedicals, Inc 0216011050	50 g
ICN16011080	MP Biomedicals, Inc 0216011080	100 g
ICN16011090	MP Biomedicals, Inc 0216011090	500 g
02-160-11091	MP Biomedicals, Inc 0216011091	1000 g

Description

Induces severe colitis (inflammatory bowel disease) in laboratory animals

Dextran sulfate sodium salt, or DSS, is a synthetic sulfated branched polysaccharide derivative of dextran that has multiple uses in biomedical and clinical research. One important property of DSS is to trigger colitis in mice and rats when administered in drinking water. DSS binds to medium-chain-length fatty acids in the colon and induces intestinal inflammation. Colitis-grade DSS (MW = 36,000 to 50,000) from MP Bio is one of the most widely used products based on peer reviewed scientific publications.

• Induces severe colitis (inflammatory bowel disease)
• Highest sulfur content – 19%
• Highest chirality - +104° of specific rotation
• Lowest pH – 6.2 at 1% solution

Specifications

• Color: White
• CAS: 9011-18-1
• Boiling Point: 310°C
• MDL Number: MFCD00081551
• Grade: Colitis Grade
• Moisture: <10%

• pH: 5 to 7.11 (1% aqueous solution)
• Physical Form: Powder
• Melting Point: 92°C
• Solubility Information: Soluble in water
• For Use With (Application): Used for inducing ulcerative colitis in animals and extensively to study colon cancer developing in relation to colonic inflammation
• Packaging: Plastic Container

Safety and Handling

storageNote1 : Store at Room Temperature (15°C to 30°C)

Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use.