Thermo Scientific Chemicals for Analytical Applications

Thermo Scientific Chemicals for Analytical Applications
Analytical Chemistry

Complete Your Analyses with Confidence

As a leader in analytical chemistry, the Thermo Scientific™ brand offers a comprehensive collection of high-purity and high-quality chemicals specifically designed to support various projects, methods, and assays while meeting the requirements of your laboratory.

Within our collection, you’ll find the right grade and chemical specification for your application, as well as products suitable for a range of analytical techniques, including sample preparation and extraction, chromatography, mass spectrometry, and trace elemental analyses.

Accuracy and reliability are important in analytical chemistry, which is why Thermo Scientific chemicals are carefully formulated. Whether you’re performing routine analyses or advanced research, you’ll be able to find a dedicated range of solvents and reagents in various purities that will meet your preparative and analytical needs.

Learn more about:

Browse Thermo Scientific Chemicals

Browse Chemicals and Consumables for PFAS Testing

Featured Products


ACS-Grade Chemicals

ACS-Grade Chemicals

Find a wide selection to meet your everyday needs.

Shop ACS-Grade Chemicals

Analytical-Grade Chemicals

Analytical-Grade Chemicals

Browse solvents, organic compounds, and more.

Shop Analytical-Grade Chemicals

NMR-Grade Chemicals

NMR-Grade Chemicals

Filter your results to find the right option quickly.

Shop NMR-Grade Chemicals

Electrophoresis-Grade Chemicals

Electrophoresis-Grade Chemicals

Meet the requirements of your application.

Shop Electrophoresis-Grade Chemicals

Chromatography & Mass Spectroscopy

Chromatography and Mass Spectrometry Chemicals and Standards

Whatever your project, method, or assay, the Thermo Scientific™ brand offers the chemicals, consumables, instrumentation, software solutions, and services you need. With products meant to support the requirements of analytical laboratories like yours, you’ll find what you’re looking for to complete your chromatography workflows, including HPLC, GC, LC-MS, and UHPLC-MS chemicals in various grades and quantities.


HPLC-Grade Solvents, Mobile Phase Buffers, Reagents, and Additives

Chemicals that are HPLC grade or above can help you achieve the performance you need from your HPLC systems, making it easier to obtain robust, repeatable results across all your liquid chromatography analyses. You’ll find a broad range of high-purity solvents, mobile phase buffers, and additives thanks to the advanced distillation process used to produce the products.

Thermo Scientific HPLC-Grade Products

  • Offer multi-purpose flexibility: With a broad range of products available, Thermo Scientific HPLC-grade chemicals are suitable for isocratic and gradient analyses, reversed phase and normal phase applications, size exclusion chromatography (SEC), and ion exchange HPLC.
  • Work for routine applications: Thermo Scientific HPLC products are suitable for use with many detectors, including UV, fluorescence, and refractive index.
  • Lower column blockages: A submicron filtration process helps you avoid column blockages caused by particulate content from chemicals.
  • Reduce background interference: Products are supplied in specially cleaned bottles or aluminum cans and blanketed with an inert gas to maintain their purity.
  • Save time and money: Use the QR code on the bottle to find product certificates of analysis (CoA) and safety data sheets (SDS) quickly and easily.
  • Meet ACS specifications: This helps you meet your requirements and have confidence in your results.

Shop HPLC-Grade Products

HPLC-Grade Solvents

Find ethanol, acetonitrile, acetone, and more.

Shop Solvents

HPLC-Grade Reagents

Browse sulfonic acids and derivatives, salts, and more.

Shop Reagents

HPLC-Grade Mobile Phase Solutions

Narrow your search for necessary solutions and salts.

Shop Mobile Phase Solutions


LC-MS-Grade Solvents, Reagents, and Mobile Phase Solutions

As new regulatory limits and instrumentation developments lead to ever-lower analyte detection limits, there is an increased need to reduce noise, which can impact the overall performance of LC-MS applications and methods.

That’s why these LC-MS products are manufactured using additional purification processes, quality control measures, and packaging innovations—to help reduce or eliminate the presence of phthalates, PEG, and other contaminants. This helps provide low mass noise levels and minimize organic contamination and metal content to meet the high-purity demands of LC-MS applications. 

Thermo Scientific LC-MS Grade Products

  • See more analytes: With very low background observed in comparison to other lower grade solvents, you’ll be able to get a better signal/noise ratio from your analytical peaks, helping you better detect your analytes even at trace levels.
  • Reduce adduct formation: Up to 17 metals are specification tested and reported in our certificate of analysis.
  • Help your system run more efficiently: Filtered at 0.1 μm, these products help reduce instrument, column, and check valve clogs.
  • Save time and money: Consider pre-made mobile phases, such as acetonitrile + 0.1% formic acid, so you can focus on other priorities in the lab.

Shop LC-MS Grade Products


UHPLC-MS-Grade Solvents and Kits

When ultimate sensitivity and purity is essential, find the products you need to deliver highly accurate results at the lowest levels of detection. Browse chemicals that are suitable for all applications and markets and are recommended for use with all chromatography systems, especially those that run columns with smaller particle sizes (less than 3 µm), such as UHPLC, micro, and nano-LC systems, and use mass spectrometry as the detection technique.

UHPLC-MS-Grade Products

  • Reduce adduct formation: These products are packaged in borosilicate bottles to help ensure extremely low leachable sodium and potassium levels and reduce adduct formation. Tight metal specifications also minimize metal ion adduct formation.
  • Help your system run more efficiently: Filtered at 0.1 μm, these products help reduce instrument, column, and check valve clogs.
  • Eliminate leachables: No fluoropolymer liners are used in the caps, helping to eliminate background interference during PFAS analyses.

GC-Grade Products

From sample preparation to separation, Thermo Scientific solvents and solvent blends have set a standard of excellence for consistent, reproducible GC performance.


Ion Chromatography Standards

Find a broad suite of chemicals to support your ion chromatography needs.

Trace Elemental Analysis

Trace Elemental Standards and High-Purity Acids

Improve your detection limits with Thermo Scientific™ Specpure™ analytical standards and solutions. Whether you’re testing for metal impurities in drugs, reporting toxic metals in food and environmental samples, or ensuring that advanced alloys meet specifications, getting accurate results is vital. Suitable for use with atomic absorption spectrometry (AAS), inductively coupled plasma (ICP), x-ray fluorescence (XRF), and other techniques, this portfolio includes a range of analytical standards and solutions that support all of your elemental analysis requirements.

Shop the Specpure Standards Collection

Single Element Standards

Shop Single Element Standards

Multi Element Standards

Shop Multi Element Standards

Atomic Absorption Spectroscopy Standards

Shop Atomic Absorption Spectroscopy Standards

ICP and ICP-MS Standards

Shop ICP and ICP-MS Standards

XRF Standards

Shop XRF Standards

Environmental Standards

Shop Environmental Standards

Viscosity Standards

Shop Viscosity Standards

Pharmaceutical Standards

Shop Pharmaceutical Standards


Featured Products

High-Volume Solvents & Blends

High-Volume Solvents & Blends

A Safe and Sustainable Chemical Handling Option

High-volume solvent and chemical blend delivery systems provide a safe and sustainable approach to an almost unlimited number of applications. This gives you an abundance of options and helps improve your productivity.

Service Benefits

Performance and Productivity

Support the laboratory, pilot plant, and production environment with a broad range of top-notch chemicals.

  • A wide variety of drum/container sizes, product grades, purities, and blends to meet your exact requirements
  • Products arrive in inert packaging, so there is no risk of chemical interactions, and they’re protected from environmental factors such as moisture and vapors

Supply and Support

Mitigate supply risk to your business with help from our chemical services team.

  • Benefit from our plentiful supply of chemicals and containers, as well as a dedicated fleet that supports our custom and bulk services
  • Use our returnable drums, barrels, and totes service, a program that’s ready to support your unique needs
  • Lean on our team to help support your requirements and provide technical or logistical assistance

Learn More About Custom and Bulk Chemical Services