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(±)-Verapamil Hydrochloride, MP Biomedicals™
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Quantity:
1 g
Description
Acts by plugging up the channels and limiting the entry of calcium into both smooth muscle cells of arteriolar walls and the cardiac muscle cells at higher doses.
- Blocks L-type Ca2+ channels in smooth and cardiac muscle
- Induces apoptosis of human primary and metastatic colon adenocarcinoma cells in vitro
- Drug resistance reversal agent acting on Pgp, e.g. decrease renal tubule elimination of digoxin
- Increases basal ATPase activity of Pgp
- Substrate of Cyp3A4 and CYP2C6
Specifications
Melting Point | 140°C to 150°C (literature) |
Quantity | 1 g |
Solubility Information | Soluble in water (7g/100mL); sparingly soluble in chloroform; soluble in ethanol (26mg/mL), isopropanol, acetone, ethyl acetate; freely soluble in methanol (>100mg/mL), DMF (>100mg/mL); practically insoluble in ether. |
Formula Weight | 491.1 |
Physical Form | Powder |
Safety and Handling
Recommended Storage | Room Temperature (15–30°C) |
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