Urelumab Recombinant Human Monoclonal Antibody, Invitrogen™

Human Recombinant Monoclonal Antibody

Supplier:  Thermo Scientific MA541939

Catalog No. PIMA541939

Description

Endotoxin level < 0.01EU/μg by LAL method Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 °C for one week. Store at -20 to -80 °C for twelve months from the date of receipt.

Urelumab has been used in trials studying the treatment of Leukemia, Multiple Myeloma, Malignant Tumors, and Cancer - Solid Tumors and B-Cell Non-Hodgkin's Lymphoma. Urelumab is a fully human antibody that targets CD137. The antibody product was developed using Medarex's UltiMAb(R) technology and was the first UltiMAb- derived antibody in clinical development by Bristol-Myers Squibb under the December 2003 agreement with Medarex.

Specifications

• Antigen: Urelumab
• Classification: Recombinant Monoclonal
• Conjugate: Unconjugated
• Gene Alias: BMS-663513
• Immunogen: Human TNFRSF9/CD137
• Quantity: 100 μg
• Primary or Secondary: Primary
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid
• Target Molecule: Chemical

• Applications: ELISA, SDS-Page
• Concentration: 2.45 mg/mL
• Formulation: 30mM histidine with 0.02% Tween 80, 10% sucrose and no preservative; pH 5.8
• Host Species: Human
• Purification Method: Protein A
• Regulatory Status: RUO
• Target Species: Chemical
• Product Type: Antibody
• Isotype: IgG4 κ