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  7. Trimethylacetyl chloride, 98+%, Thermo Scientific Chemicals

Trimethylacetyl chloride, 98+%, Thermo Scientific Chemicals

Catalog Number AAA15051AE
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Quantity:
100 mL
500 mL
2500 mL
3282-30-2
C5H9ClO
120.58
MFCD00000709
JVSFQJZRHXAUGT-UHFFFAOYSA-N
pivaloyl chloride, trimethylacetyl chloride, propanoyl chloride, 2,2-dimethyl, pivalyl chloride, pivaloylchloride, 2,2-dimethylpropionyl chloride, pivalic acid chloride, pivalolyl chloride, unii-jq82j0o21t, 2,2-dimethylpropionylchloride
62493
2,2-dimethylpropanoyl chloride
CC(C)(C)C(Cl)=O
3282-30-2
C5H9ClO
120.58
MFCD00000709
JVSFQJZRHXAUGT-UHFFFAOYSA-N
pivaloyl chloride, trimethylacetyl chloride, propanoyl chloride, 2,2-dimethyl, pivalyl chloride, pivaloylchloride, 2,2-dimethylpropionyl chloride, pivalic acid chloride, pivalolyl chloride, unii-jq82j0o21t, 2,2-dimethylpropionylchloride
62493
2,2-dimethylpropanoyl chloride
CC(C)(C)C(Cl)=O

Description

Trimethylacetyl chloride is used as a precursor in the preparation of tert-butyl peroxypivalate, guttiferon A derivatives, which is potential for the treatment of malaria. It is used as a raw material in the production of synthetic acidamide medicament and phenol ester medicament. In addition to this, it is used for the synthesis of active pharmaceutical ingredients such as aminobenzylpenicilin, cephalexin, cefazolin, dipivefrin and dipivalyl epinephrine. It is also used in heavy polymerization, N-acylating agent for amines, Schiff bases, pyrrolidinones as well as an O-acylating agent for alcohols, lactones and saccharides.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Trimethylacetyl chloride is used as a precursor in the preparation of tert-butyl peroxypivalate, guttiferon A derivatives, which is potential for the treatment of malaria. It is used as a raw material in the production of synthetic acidamide medicament and phenol ester medicament. In addition to this, it is used for the synthesis of active pharmaceutical ingredients such as aminobenzylpenicilin, cephalexin, cefazolin, dipivefrin and dipivalyl epinephrine. It is also used in heavy polymerization, N-acylating agent for amines, Schiff bases, pyrrolidinones as well as an O-acylating agent for alcohols, lactones and saccharides.

Solubility
Miscible with acetonitrile.

Notes
Moisture sensitive. Incompatible withalcohols, oxidizing agents and strong bases.
TRUSTED_SUSTAINABILITY
Melting Point -57°C
Density 0.985
Boiling Point 105°C to 106°C
Flash Point 8°C (46°F)
Odor Pungent
Refractive Index 1.412
Quantity 100 mL
UN Number UN2438
Beilstein 385668
Sensitivity Moisture sensitive
Solubility Information Miscible with acetonitrile.
Formula Weight 120.58
Percent Purity ≥98%
Chemical Name or Material Trimethylacetyl chloride
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Safety and Handling

Hazard Category H225-H290-H302-H314-H330
Hazard Statement GHS H Statement
H225-H330-H314-H318-H302
Highly flammable liquid and vapour.
Fatal if inhaled.
Causes severe skin burns and eye damage.
Causes serious eye damage.
Harmful if swallowed.
Precautionary Statement P210-P233-P234-P235-P240-P241-P242-P243-P260-P264b-P270-P271-P280-P284-P303+P361+P353-P304+P340-P305+P351+P338-P310-P330-P331-P363-P370+P378q-P390-P501c
DOTInformation Transport Hazard Class: 6.1; Packing Group: I; Proper Shipping Name: TRIMETHYLACETYL CHLORIDE
EINECSNumber 221-921-6
TSCA Yes
Recommended Storage Ambient temperatures
SDS

RUO – Research Use Only

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