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TPCA-1, Tocris Bioscience™

Catalog Number 255910
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Quantity:
10 mg
This item is not returnable. View return policy
507475-17-4
C12H10FN3O2S
279.289
SAYGKHKXGCPTLX-UHFFFAOYSA-N
tpca-1, 5-4-fluorophenyl-2-ureidothiophene-3-carboxamide, ikk-2 inhibitor iv, tpca1, 5-p-fluorophenyl-2-ureido thiophene-3-carboxamide, 2-carbamoylamino-5-4-fluorophenyl thiophene-3-carboxamide, insolution ikk-2 inhibitor iv, 3qfv, ikk2 inhibitor iv, d0e0xv
9903786
2-(carbamoylamino)-5-(4-fluorophenyl)thiophene-3-carboxamide
C1=CC(=CC=C1C2=CC(=C(S2)NC(=O)N)C(=O)N)F
This item is not returnable. View return policy
507475-17-4
C12H10FN3O2S
279.289
SAYGKHKXGCPTLX-UHFFFAOYSA-N
tpca-1, 5-4-fluorophenyl-2-ureidothiophene-3-carboxamide, ikk-2 inhibitor iv, tpca1, 5-p-fluorophenyl-2-ureido thiophene-3-carboxamide, 2-carbamoylamino-5-4-fluorophenyl thiophene-3-carboxamide, insolution ikk-2 inhibitor iv, 3qfv, ikk2 inhibitor iv, d0e0xv
9903786
2-(carbamoylamino)-5-(4-fluorophenyl)thiophene-3-carboxamide
C1=CC(=CC=C1C2=CC(=C(S2)NC(=O)N)C(=O)N)F

Description

Potent, selective inhibitor of IKKβ

Potent, selective inhibitor of IκB kinase (IKK) β (IC50 = 17.9 nM) that displays > 22-fold selectivity over IKKα and > 550-fold selectivity over other kinases and enzymes. Inhibits production of pro-inflammatory cytokines in vitro and in vivo and inhibits NF-κB nuclear localization. Reduces the severity and onset of collagen-induced arthritis; anti-inflammatory.
Quantity 10 mg
Formula Weight 279.29
Percent Purity >97%
Chemical Name or Material TPCA-1

Safety and Handling

Recommended Storage Desiccate at -20°C
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