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TPCA-1, Tocris Bioscience™
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Quantity:
10 mg
Description
Potent, selective inhibitor of IκB kinase (IKK) β (IC50 = 17.9 nM) that displays > 22-fold selectivity over IKKα and > 550-fold selectivity over other kinases and enzymes. Inhibits production of pro-inflammatory cytokines in vitro and in vivo and inhibits NF-κB nuclear localization. Reduces the severity and onset of collagen-induced arthritis; anti-inflammatory.
Specifications
Quantity | 10 mg |
Formula Weight | 279.29 |
Percent Purity | >97% |
Chemical Name or Material | TPCA-1 |
Safety and Handling
Recommended Storage | Desiccate at -20°C |
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