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  8. Thiamphenicol, Thermo Scientific Chemicals

Thiamphenicol, Thermo Scientific Chemicals

Catalog Number AAJ6357506
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Quantity:
1 g
5 g
25 g
15318-45-3
C12H15Cl2NO5S
356.214
MFCD00467983
OTVAEFIXJLOWRX-NXEZZACHSA-N
thiamphenicol, thiophenicol, thiamcol, +-thiamphenicol, raceophenidol, thiocymetin, dextrosulphenidol, thiamphenicolum, d-thiocymetin, d-thiophenicol
27200
CHEBI:32215
2,2-dichloro-N-[(1R,2R)-1,3-dihydroxy-1-(4-methylsulfonylphenyl)propan-2-yl]acetamide
CS(=O)(=O)C1=CC=C(C=C1)C(C(CO)NC(=O)C(Cl)Cl)O
15318-45-3
C12H15Cl2NO5S
356.214
MFCD00467983
OTVAEFIXJLOWRX-NXEZZACHSA-N
thiamphenicol, thiophenicol, thiamcol, +-thiamphenicol, raceophenidol, thiocymetin, dextrosulphenidol, thiamphenicolum, d-thiocymetin, d-thiophenicol
27200
CHEBI:32215
2,2-dichloro-N-[(1R,2R)-1,3-dihydroxy-1-(4-methylsulfonylphenyl)propan-2-yl]acetamide
CS(=O)(=O)C1=CC=C(C=C1)C(C(CO)NC(=O)C(Cl)Cl)O

Description

The methyl-sulfonyl analogue of chloramphenicol

Thiamphenicol is used to treat chancroid in men and uncomplicated gonorrhea. It is used in studies of bacterial protein synthesis at the level of peptidyl transferase activity associated with the 23S rRNA of the 50S ribosomal subunit. It is used to study chloraniphenicol-thiamphenicol-resistance and the use of fluorinated analogs when resistance is encountered. Its main advantage over chloramphenicol is that it has never been associated with aplastic anaemia.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Thiamphenicol is used to treat chancroid in men and uncomplicated gonorrhea. It is used in studies of bacterial protein synthesis at the level of peptidyl transferase activity associated with the 23S rRNA of the 50S ribosomal subunit. It is used to study chloraniphenicol-thiamphenicol-resistance and the use of fluorinated analogs when resistance is encountered. Its main advantage over chloramphenicol is that it has never been associated with aplastic anaemia.

Solubility
Soluble in acetonitrile or DMF. Slightly soluble in water

Notes
Research Use only: Not intended for animal or human diagnostic or therapeutic use.
TRUSTED_SUSTAINABILITY
Color White to Yellow
Quantity 5 g
Beilstein 2819542
Merck Index 14,9301
Solubility Information Soluble in acetonitrile or DMF; Slightly soluble in water
Formula Weight 356.22
Physical Form Powder
Chemical Name or Material Thiamphenicol

Safety and Handling

EINECSNumber 239-355-3
RTECSNumber AB6680000
TSCA No
Recommended Storage Ambient temperatures
SDS

RUO – Research Use Only

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