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  6. Tetracycline, Thermo Scientific Chemicals

Tetracycline, Thermo Scientific Chemicals

Catalog Number AAJ6171406
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Quantity:
5 g
25 g
100 g
60-54-8
C22H24N2O8
444.44
MFCD00151232
JYHCQVWYCGHXGP-BPPSBWQWSA-N
54675776
CN(C)[C@H]1[C@@H]2C[C@H]3C(=C(O)C4=C(O)C=CC=C4[C@@]3(C)O)C(=O)[C@]2(O)C(=O)\C(=C(\N)O)C1=O
60-54-8
C22H24N2O8
444.44
MFCD00151232
JYHCQVWYCGHXGP-BPPSBWQWSA-N
54675776
CN(C)[C@H]1[C@@H]2C[C@H]3C(=C(O)C4=C(O)C=CC=C4[C@@]3(C)O)C(=O)[C@]2(O)C(=O)\C(=C(\N)O)C1=O

Description

Tetracycline, Deschlorobiomycin, CAS # 60-54-8, is a broad-spectrum napthacene antibiotic that inhibits bacterial growth.

Tetracycline is used for treatment of chronic inflammatory cells. Tetracycline derivatives induce apoptosis in osteoclasts, Jurkat T lymphocyte cells and in cultured monocytes and macrophages. It is a compound that has been shown to induce apoptosis in various cells.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

• Tetracycline is a semisynthetic compound derived from chlortetracycline, an isolate from Streptomyces aureofaciens
• Tetracycline is a broad-spectrum bacteriostatic that inhibits polypeptide formation by binding the 30S ribosomal subunit and preventing aminoacyl tRNA-mRNA complex formation
• It may have other bactericidal properties such as limited binding to the 50S subunit

Application

• Tetracycline has been shown to exhibit antiprotozoal properties
• It can be used to kill both gram-positive and gram-negative bacteria
• It is suitable for use in laboratory applications in resistance gene testing and research on infection

TRUSTED_SUSTAINABILITY
Type Tetracycline
Physical Form Crystalline Powder
Melting Point 172°C to 174°C
Beilstein 2230417
Merck Index 14,9196
Solubility Information Limited solubility in water; Soluble in 1M HCl with heating.
IUPAC Name (2Z,4S,4aS,5aS,6S,12aS)-2-[amino(hydroxy)methylidene]-4-(dimethylamino)-6,10,11,12a-tetrahydroxy-6-methyl-1,2,3,4,4a,5,5a,6,12,12a-decahydrotetracene-1,3,12-trione
Formula Weight 444.43
Color Yellow
Quantity 5 g
Chemical Name or Material Tetracycline
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Safety and Handling

Hazard Category H302
Hazard Statement GHS H Statement
H302
Harmful if swallowed.
Precautionary Statement P264b-P270-P301+P312-P330-P501c
EINECSNumber 200-481-9
RTECSNumber QI8750000
TSCA No
Recommended Storage Keep cold
SDS

RUO – Research Use Only

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