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  7. Taxol, Tocris Bioscience™

Taxol, Tocris Bioscience™

Catalog Number 109750
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
33069-62-4
C47H51NO14
853.92
MFCD00869953
RCINICONZNJXQF-VAZQATRQSA-N
paclitaxel, taxol, taxol a, abraxane, paxene, paxceed, plaxicel, yewtaxan, onxol, ebetaxel
133640187
(1S,2S,4S,7R,9S,10S,12R,15S)-4,12-bis(acetyloxy)-1,9-dihydroxy-15-{[(2R,3S)-2-hydroxy-3-phenyl-3-(phenylformamido)propanoyl]oxy}-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo[11.3.1.0³,¹⁰.0⁴,⁷]heptadec-13-en-2-yl benzoate
CC(=O)O[C@@H]1C2=C(C)[C@H](C[C@@](O)([C@@H](OC(=O)C3=CC=CC=C3)C3[C@@]4(CO[C@@H]4C[C@H](O)[C@@]3(C)C1=O)OC(C)=O)C2(C)C)OC(=O)[C@H](O)[C@@H](NC(=O)C1=CC=CC=C1)C1=CC=CC=C1
This item is not returnable. View return policy
33069-62-4
C47H51NO14
853.92
MFCD00869953
RCINICONZNJXQF-VAZQATRQSA-N
paclitaxel, taxol, taxol a, abraxane, paxene, paxceed, plaxicel, yewtaxan, onxol, ebetaxel
133640187
(1S,2S,4S,7R,9S,10S,12R,15S)-4,12-bis(acetyloxy)-1,9-dihydroxy-15-{[(2R,3S)-2-hydroxy-3-phenyl-3-(phenylformamido)propanoyl]oxy}-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo[11.3.1.0³,¹⁰.0⁴,⁷]heptadec-13-en-2-yl benzoate
CC(=O)O[C@@H]1C2=C(C)[C@H](C[C@@](O)([C@@H](OC(=O)C3=CC=CC=C3)C3[C@@]4(CO[C@@H]4C[C@H](O)[C@@]3(C)C1=O)OC(C)=O)C2(C)C)OC(=O)[C@H](O)[C@@H](NC(=O)C1=CC=CC=C1)C1=CC=CC=C1

Description

Promotes assembly and inhibits disassembly of microtubules

Taxol, also known as paclitaxel, promotes and stabilizes tubulin polymerization, causing cell cycle arrest. In CCRF-HSB-2 cells, Taxol induces autocatalytic activation of caspase-10, triggering apoptosis. Taxol is an antitumor agent. In a mouse model of bladder cancer Taxol decreases tumor growth. Taxol also prolongs survival of mice transplanted with human ovarian carcinoma xenografts. Taxol improves neurological outcome and magnetic resonance imaging biomarkers after traumatic brain injury in mice.
Quantity 50 mg
Formula Weight 853.92
Percent Purity >99%
Chemical Name or Material Taxol

Safety and Handling

Recommended Storage Store at +4°C
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