Thermo Scientific™ SMART Digest™ Trypsin Kits

Catalog Number	Mfr. No.	Description
03-150-404	Thermo Scientific™ 60109101	Smart Digest Kit EA	Smart Digest Kit EA
03-251-893	Thermo Scientific™ 60109101BLPH	Smart Diget Kit With Bulk Resin, Low pH	Smart Diget Kit With Bulk Resin, Low pH
03-251-897	Thermo Scientific™ 60109101LPH	Smart Diget Kit With Collection Plate, Low pH	Smart Diget Kit With Collection Plate, Low pH
03-150-406	Thermo Scientific™ 60109103	Smart Digest Kit w/ SOLAµ SPE plate	Smart Digest Kit w/ SOLAµ SPE plate
03-251-894	Thermo Scientific™ 60109101MBLPH	Smart Digest Kit, magnetic Bead, Bulk, Low pH	Smart Digest Kit, magnetic Bead, Bulk, Low pH
03-150-405	Thermo Scientific™ 60109102	Smart Digest Kit w/ Filter plate	Smart Digest Kit w/ Filter plate
03-375-364	Thermo Scientific™ 60109101B	N/A
03-253-935	Thermo Scientific™ 60113101LPH	Soluble Smart Digest Kit Trypsin, Low pH Buffer	Soluble Smart Digest Kit Trypsin, Low pH Buffer
03-252-203	Thermo Scientific™ 60109101MB	N/A
03-252-204	Thermo Scientific™ 60109102B	N/A
13-622-452	Thermo Scientific™ 60109102MB	N/A
03-252-205	Thermo Scientific™ 60109103B	N/A
03-251-711	Thermo Scientific™ 60113101	N/A
03-252-206	Thermo Scientific™ 60109103MB	N/A
03-170-489	Thermo Scientific™ 60113101LS	N/A

Description

Obtain high quality analytical results from protein digests using Thermo Scientific™ SMART Digest™ Kits. A significant advance in sample preparation for biopharmaceutical protein research, the kits provide fast and simple protein digestion with high reproducibility, high sensitivity, and high levels of data quality in a format that's compatible with automation. The SMART Digest Kits are a significant improvement over current in-solution protein digestion technologies, which are not reproducible, have poor sensitivity, and employ protracted methodologies not amenable to automation.

Trypsin Protein Digestion

SMART Digest kits enable you to characterize and quantitate proteins faster, easier, and quicker than ever before. This version of the kit uses trypsin, which cleaves peptides on the C-terminal side of lysine and arginine amino acid residues.

Easy and simple

• Significantly increased speed of sample processing
• Simple process
• Easily automate entire protocol for high-throughput processing

Reliable Results

• Increased reproducibility over existing protocols
• Higher sensitivity
• Higher data confidence

Significantly Reduces Sample Preparation Time

Typically it takes less than 60 minutes (dependent on sample complexity) to achieve full digestion, whereas an in-solution digest can take up to 24 hours.

Cleaner Samples

Reduction in the number of chemicals used and the immobilized trypsin design helps mitigate against chemically induced post translational modifications (PTMs) and autolysis. This results in results which are easier to interpret.

Couple with SOLAµ SPE Plates for Desalting

When used with the SMART Digest kits for desalting, Thermo Scientific™ SOLAµ™ SPE solid phase extraction plates provide a fast, easy-to-use, robust, and easily automatable sample preparation solution for analysis of biomolecules.