Thermo Scientific™ SMART Digest™ Trypsin Kits

Catalog Number	Mfr. No.	Description	Format	Includes
03-150-404	Thermo Scientific™ 60109101	SMART Digest Trypsin Kit, with Collection plate	SMART Digest Resin Pre-filled into PCR Tubes	SMART Digest Resin Pre-filled into 96 PCR Tubes, Collection Plate
03-251-893	Thermo Scientific™ 60109101BLPH	Smart digest kit with bulk resin , low pH	SMART Digest Low pH Resin Pre-filled into PCR Tubes	SMART Digest Low pH Resin Pre-filled into 96 PCR Tubes, Collection Plate
03-251-897	Thermo Scientific™ 60109101LPH	Smart digest kit with collection plate, low pH	SMART Digest Low pH Resin Pre-filled into PCR Tubes	SMART Digest Low pH Resin Pre-filled into 96 PCR Tubes, Collection Plate
03-150-406	Thermo Scientific™ 60109103	SMART Digest Trypsin Kit, with SOLAµ/collection plate	SMART Digest Resin Pre-filled into PCR Tubes	SMART Digest Resin Pre-filled into 96 PCR Tubes, Collection Plate, SOLAµ SPE Plate
03-251-894	Thermo Scientific™ 60109101MBLPH	Smart digest kit, magnectic bead, bulk, low pH	SMART Digest Low pH Resin Pre-filled into PCR Tubes	SMART Digest Low pH Resin Pre-filled into 96 PCR Tubes, Collection Plate
03-150-405	Thermo Scientific™ 60109102	SMART Digest Trypsin Kit, with Filter/Collection plate	SMART Digest Resin Pre-filled into PCR Tubes	SMART Digest Resin Pre-filled into 96 PCR Tubes, Collection Plate, Filter Plate
03-375-364	Thermo Scientific™ 60109101B	SMART Digest Trypsin Kit, Bulk Resin option	SMART Digest Resin, Bulk Non-magnetic	Bulk Non-magnetic SMART Digest Resin, SMART Digest Buffer
03-253-935	Thermo Scientific™ 60113101LPH	Soluble smart digest kit, trypsin, low pH buffer	SMART Digest Low pH Buffer	SMART Digest Low pH Buffer
03-252-203	Thermo Scientific™ 60109101MB	SMART Digest Trypsin Kit, Magnetic Bulk Resin option	SMART Digest Resin, Bulk Magnetic	Bulk Magnetic SMART Digest Resin, SMART Digest Buffer
03-252-204	Thermo Scientific™ 60109102B	SMART Digest Trypsin Kit, Bulk Resin option with Filter/Collection plate	SMART Digest Resin, Bulk Non-magnetic	Bulk Non-magnetic SMART Digest Resin, SMART Digest Buffer, Collection Plate, Filter Plate
13-622-452	Thermo Scientific™ 60109102MB	SMART Digest Trypsin Kit, Magnetic Bulk Resin option with Filter/Collection plate	SMART Digest Resin, Bulk Magnetic	Bulk Magnetic SMART Digest Resin, SMART Digest Buffer, Collection Plate, Filter Plate
03-252-205	Thermo Scientific™ 60109103B	SMART Digest Trypsin Kit, Bulk Resin option with SOLAµ/collection plate	SMART Digest Resin, Bulk Non-magnetic	Bulk Non-magnetic SMART Digest Resin, SMART Digest Buffer, Collection Plate, SOLAµ SPE Plate
03-251-711	Thermo Scientific™ 60113101	SMART Digest Trypsin Kit, Soluble	SMART Digest Soluble Trypsin	SMART Digest Soluble Trypsin, SMART Digest Buffer, Collection Plate
03-252-206	Thermo Scientific™ 60109103MB	SMART Digest Trypsin Kit Magnetic Bulk Resin option with SOLAµ/collection plate	SMART Digest Resin, Bulk Magnetic	Bulk Magnetic SMART Digest Resin, SMART Digest Buffer, Collection Plate, SOLAµ SPE Plate
03-170-489	Thermo Scientific™ 60113101LS	SMART Digest Trypsin Kit, Soluble Low Salt

Description

Obtain high quality analytical results from protein digests using Thermo Scientific™ SMART Digest™ Kits. A significant advance in sample preparation for biopharmaceutical protein research, the kits provide fast and simple protein digestion with high reproducibility, high sensitivity, and high levels of data quality in a format that's compatible with automation. The SMART Digest Kits are a significant improvement over current in-solution protein digestion technologies, which are not reproducible, have poor sensitivity, and employ protracted methodologies not amenable to automation.

Trypsin Protein Digestion

SMART Digest kits enable you to characterize and quantitate proteins faster, easier, and quicker than ever before. This version of the kit uses trypsin, which cleaves peptides on the C-terminal side of lysine and arginine amino acid residues.

Easy and simple

• Significantly increased speed of sample processing
• Simple process
• Easily automate entire protocol for high-throughput processing

Reliable Results

• Increased reproducibility over existing protocols
• Higher sensitivity
• Higher data confidence

Significantly Reduces Sample Preparation Time

Typically it takes less than 60 minutes (dependent on sample complexity) to achieve full digestion, whereas an in-solution digest can take up to 24 hours.

Cleaner Samples

Reduction in the number of chemicals used and the immobilized trypsin design helps mitigate against chemically induced post translational modifications (PTMs) and autolysis. This results in results which are easier to interpret.

Couple with SOLAµ SPE Plates for Desalting

When used with the SMART Digest kits for desalting, Thermo Scientific™ SOLAµ™ SPE solid phase extraction plates provide a fast, easy-to-use, robust, and easily automatable sample preparation solution for analysis of biomolecules.