Thermo Scientific™ Slide-A-Lyzer™ Dialysis Cassettes, 7K MWCO

Remove salts and contaminants and maximize sample recovery using this semi-permeable membrane with a 7,000-Dalton protein MW cut-off (7K MWCO).

Catalog Number	Mfr. No.	Description	Sample Volume (Metric)
PI66373	Thermo Scientific™ 66373	Dialysis Cassettes	0.5 mL
PI66370	Thermo Scientific™ 66370	Dialysis Cassettes	3 mL
PI66372	Thermo Scientific™ 66372	Dialysis Cassette Kit	3 mL
PI66710	Thermo Scientific™ 66710	Dialysis Cassettes	12 mL
PI66707	Thermo Scientific™ 66707	Dialysis Cassette Kit	12 mL

Description

Slide-A-Lyzer Dialysis Cassettes (7K MWCO) facilitate the simple and effective removal of salts and small contaminants from proteins or other macromolecules greater than 7,000 Daltons. They are available in four sizes to accommodate sample volumes between 0.5 and 12 mL. These devices are easier to use than traditional dialysis tubing, providing faster buffer exchange, and more complete sample recovery.

Slide-A-Lyzer cassettes can be used for a wide range of applications including low-molecular weight contaminant removal, buffer exchange, desalting, equilibrium dialysis, and sample concentration. Liquid samples are easily added and removed by penetrating the self-sealing gasket with a hypodermic needle attached to a syringe. No knots, clips, or caps are needed to seal the units and prevent leaking and sample-loss during the dialysis procedure.

Slide-A-Lyzer Dialysis Cassettes are constructed from two sheets of low-binding, regenerated-cellulose dialysis membrane that are hermetically sealed on either side of a silicone-like gasket inside an inert plastic frame. The membrane and cassette materials are compatible with most common laboratory chemicals and buffers.

Features of Slide-A-Lyzer Dialysis Cassettes:
• Easy to use—no knots or clamps are needed; just inject sample into cassette and begin dialysis
• Fast dialysis—flat cassette chamber with two membranes provides high surface-area to volume ratio that maximizes diffusion rate compared to cylindrical dialysis tubing
• High recovery—rectangular cassette design maximizes recovery of entire sample volume via any one of the four corner injection ports
• Four cassette sizes—select the cassette that best suits your sample volume
• Color-coded—green cassette frame specifies cassettes with the 7,000 MW pore size membrane

Membrane specifications:
• Composition: regenerated cellulose synthesized by the viscose method
• Thickness: 0.9 to 1.2 mil (22.5 to 30 μm)
• Hydration time required before use: 2 minutes
• Glycerol content: 13%
• Sulfur content: 0.1 to 0.15%
• Heavy metals content: trace

Volume ranges:
• 0.5 mL = 0.1 to 0.5 mL
• 3 mL = 0.5 to 3 mL
• 12 mL = 3 to 12 mL

Specifications

• Content And Storage: Store at room temperature
• Membrane: Cellulose Membrane, Dialysis
• MWCO: 7.0 kDa

• Purification Target: Buffer Exchange, Protein
• Format: Cassette
• Product Line: Slide-A-Lyzer™

Slide-A-Lyzer Dialysis Cassette Technology is protected by U.S. Patent 5,503,741.