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Thermo Scientific™ Silylation Grade Solvents

Use specially manufactured and packaged Thermo Scientific™ Silylation Grade Solvents to meet the exacting needs of silylation and other sensitive derivatization reactions.

Supplier:  Thermo Scientific™ TS27860

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Catalog No. PI27860

Item Discontinued This item has been discontinued by the supplier and is no longer available. Please reach out to your sales representative.


Description

Description

Use specially manufactured and packaged Thermo Scientific™ Silylation Grade Solvents to meet the exacting needs of silylation and other sensitive derivatization reactions. They are purified, dried, and packaged under nitrogen in convenient Thermo Scientific™ Hypo-Vial™ Sample Storage Vials, and are supplied with elastomer septa to enable immediate access to the sample without exposure to moisture and oxygen. Use polar solvents (acetonitrile, dimethylformamide, dimethylsulfoxide, pyridine, tetrahyrdrofuran) to facilitate reactions; nonpolar organic solvents may be used but will not accelerate the rate of reaction.

Recommended Use

Avoid water or alcohol, as TMS reagents react with active hydrogen.

Avoid enolizable ketones.

Use dimethylformamide for steroids and other large molecules.

Use dimethylsulfoxide to prepare TMS derivatives of tertiary alcohols and some compounds with low solubility in other silylation solvents.

Pyridine is an excellent solvent and reaction medium for MS reactions and is an HCI acceptor in reactions involving organochlorosilanes.

Other commonly used solvents include tetrahydrofuran and acetonitrile.

TRUSTED_SUSTAINABILITY
Specifications

Specifications

GC
Tetrahydrofuran (THF); 50 mL
98 to 100%
Flammable, Harmful, Irritant
Tetrahydrofuran
Room Temperature
SDS
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Documents

Product Certifications
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