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  8. SB 271046 hydrochloride, Tocris Bioscience™

SB 271046 hydrochloride, Tocris Bioscience™

Catalog Number 336850
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
209481-20-9
C20H23Cl2N3O3S2
488.442
RMXZRJYGJMSDQK-UHFFFAOYSA-N
sb 271046 hydrochloride, 5-chloro-n-4-methoxy-3-piperazin-1-yl phenyl-3-methylbenzo b thiophene-2-sulfonamide hydrochloride, 5-chloro-n-4-methoxy-3-piperazin-1-yl-phenyl-3-methyl-2-benzo-thiophenesulfonamide hydrochloride, 5-chloro-n-4-methoxy-3-1-piperazinyl phenyl-3-methyl-benzo b thiophen-2-sulfonamide hydrochloride, acmc-20ekpy, 5-chloro-n-4-methoxy-3-piperazin-1-yl phenyl-3-methyl-1-benzothiophene-2-sulfonamide hydrochloride, unii-x289jnp23g, sb-271046 hydrochloride, c20h22cln3o3s2.clh
6918455
5-chloro-N-(4-methoxy-3-piperazin-1-ylphenyl)-3-methyl-1-benzothiophene-2-sulfonamide;hydrochloride
CC1=C(SC2=C1C=C(C=C2)Cl)S(=O)(=O)NC3=CC(=C(C=C3)OC)N4CCNCC4.Cl
This item is not returnable. View return policy
209481-20-9
C20H23Cl2N3O3S2
488.442
RMXZRJYGJMSDQK-UHFFFAOYSA-N
sb 271046 hydrochloride, 5-chloro-n-4-methoxy-3-piperazin-1-yl phenyl-3-methylbenzo b thiophene-2-sulfonamide hydrochloride, 5-chloro-n-4-methoxy-3-piperazin-1-yl-phenyl-3-methyl-2-benzo-thiophenesulfonamide hydrochloride, 5-chloro-n-4-methoxy-3-1-piperazinyl phenyl-3-methyl-benzo b thiophen-2-sulfonamide hydrochloride, acmc-20ekpy, 5-chloro-n-4-methoxy-3-piperazin-1-yl phenyl-3-methyl-1-benzothiophene-2-sulfonamide hydrochloride, unii-x289jnp23g, sb-271046 hydrochloride, c20h22cln3o3s2.clh
6918455
5-chloro-N-(4-methoxy-3-piperazin-1-ylphenyl)-3-methyl-1-benzothiophene-2-sulfonamide;hydrochloride
CC1=C(SC2=C1C=C(C=C2)Cl)S(=O)(=O)NC3=CC(=C(C=C3)OC)N4CCNCC4.Cl

Description

Selective, orally active 5-HT6 antagonist

Selective, orally active 5-HT6 antagonist (pKi values are 9.02-8.92, 6.55, 6.35, 6.27, 6.05, 5.95, 5.76, 5.73, 5.62, 5.55, 5.41, 5.39, 5.27 and < 4.99 at 5-HT6, 5-HT1D, 5-HT1A, D3, 5-HT1B, 5-HT1F, α1B, 5-HT2C, 5-HT2A, D2, 5-HT2B, 5-HT7, 5-HT4 and 5-HT1E respectively) and is > 200-fold selective over 55 other receptors, enzymes and ion channels. Increases extracellular glutamate and aspartate in the frontal cortex, and exhibits anticonvulsant activity (EC50 = 0.16 μM).
Quantity 50 mg
Formula Weight 488.45
Percent Purity >99%
Chemical Name or Material SB 271046 hydrochloride

Safety and Handling

Recommended Storage Desiccate at Room Temperature
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