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SB 271046 hydrochloride, Tocris Bioscience™
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Quantity:
10 mg
50 mg
Description
Selective, orally active 5-HT6 antagonist (pKi values are 9.02-8.92, 6.55, 6.35, 6.27, 6.05, 5.95, 5.76, 5.73, 5.62, 5.55, 5.41, 5.39, 5.27 and < 4.99 at 5-HT6, 5-HT1D, 5-HT1A, D3, 5-HT1B, 5-HT1F, α1B, 5-HT2C, 5-HT2A, D2, 5-HT2B, 5-HT7, 5-HT4 and 5-HT1E respectively) and is > 200-fold selective over 55 other receptors, enzymes and ion channels. Increases extracellular glutamate and aspartate in the frontal cortex, and exhibits anticonvulsant activity (EC50 = 0.16 μM).
Specifications
Quantity | 50 mg |
Formula Weight | 488.45 |
Percent Purity | >99% |
Chemical Name or Material | SB 271046 hydrochloride |
Safety and Handling
Recommended Storage | Desiccate at Room Temperature |
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