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  7. RJR 2429 dihydrochloride, Tocris Bioscience™

RJR 2429 dihydrochloride, Tocris Bioscience™

Catalog Number 127150
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
1021418-53-0
C12H18Cl2N2
261.19
PIUNXHHZRIUBOV-UHFFFAOYSA-N
rjr 2429 dihydrochloride, +/--2-3-pyridinyl-1-azabicyclo 2.2.2 octane dihydrochloride
56972204
2-pyridin-3-yl-1-azabicyclo[2.2.2]octane;dihydrochloride
C1CN2CCC1CC2C3=CN=CC=C3.Cl.Cl
This item is not returnable. View return policy
1021418-53-0
C12H18Cl2N2
261.19
PIUNXHHZRIUBOV-UHFFFAOYSA-N
rjr 2429 dihydrochloride, +/--2-3-pyridinyl-1-azabicyclo 2.2.2 octane dihydrochloride
56972204
2-pyridin-3-yl-1-azabicyclo[2.2.2]octane;dihydrochloride
C1CN2CCC1CC2C3=CN=CC=C3.Cl.Cl

Description

Nicotinic receptor agonist

Potent nAChR agonist that displays selectivity for α4β2 (Ki = 1 nM) and α1βγδ subtypes (EC50 values are 297 and 55 nM respectively). Induces dopamine release from striatal neurons (EC50 = 2 nM) and inhibits ion flux in thalamic neurons (IC50 = 154 nM). Also putative α3β4 agonist that potentiates catecholamine release.
Quantity 50 mg
Formula Weight 261.19
Percent Purity >98%
Chemical Name or Material RJR 2429 dihydrochloride

Safety and Handling

Recommended Storage Desiccate at Room Temperature
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