Retinol, 95%, synthetic, Thermo Scientific Chemicals

Description

All-trans-retinol, Vitamin A, retinol, CAS # 68-26-8, is a fat-soluble vitamin that binds retinoid receptors within cells.

It induces cell differentiation and apoptosis of some cancer cell types and inhibiting carcinogenesis. It plays an essential role in metabolic functioning of the retina, the growth of and differentiation of epithelial tissue, the growth of bone, reproduction, and the immune response. It acts as a ligand for both the retinoic acid receptor (RAR) and the retinoid X receptor (RXR) that act as transcription factors to regulate the growth and differentiation of normal and malignant cells.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General description
• All-trans-retinol, commonly known as Vitamin A, is a fat-soluble essential nutrient
• All-trans-retinol is involved in hormonal signaling via the retinoid receptors
• It is an important regulator of cell division and apoptosis
• Deficiency can lead to vision, bone, immune, and skin disorders

Applications
• Suitable for research on cell differentiation, embryonic development, immunology and more
• Laboratory grade quality, for research use only

Specifications

• Color: White to Yellow
• Quantity: 100 mg
• Beilstein: 403040
• Sensitivity: Light and moisture sensitive
• Merck Index: 14,10013
• Synonym: retinol, vitamin a, all-trans-retinol, vitamin a1, alphalin, axerophthol, vitamin a alcohol, oleovitamin a, chocola a, alphasterol
• Solubility Information: Practically insoluble aq. soln. or glycerol; soluble in absolute alcohol, methanol, chloroform,ether,fats and oils.
• SMILES: C\C(=C/CO)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C
• IUPAC Name: (2 E,4 E,6 E,8 E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohexen-1-yl)nona-2,4,6,8-tetraen-1-ol
• Molecular Weight (g/mol): 286.46
• Formula Weight: 286.46
• Percent Purity: 95%
• Physical Form: Crystalline Solid
• Chemical Name or Material: Retinol, synthetic

Safety and Handling

Hazard Category	H302-H315-H319-H361d-H500
Hazard Statement	GHS H Statement H302-H315-H319 Harmful if swallowed. Causes skin irritation. Causes serious eye irritation.
Precautionary Statement	P201-P202-P264b-P270-P280-P280i-P301+P312-P302+P352-P305+P351+P338-P308+P313-P330-P332+P313-P362-P501c
EINECSNumber	200-683-7
RTECSNumber	VH6750000
TSCA	Yes
Recommended Storage	Store at -20°C; Store under Nitrogen

SDS

RUO – Research Use Only