Thermo Scientific™ ProPac™ WCX-10 HPLC Columns

Catalog Number	Mfr. No.	Particle Size	Diameter (Metric)	Length (Metric)	Column Format
DX054993	Thermo Scientific™ 054993	10 μm	4 mm	250 mm	Analytical Column
DX063472	Thermo Scientific™ 063472	10 μm	2 mm	250 mm	Analytical Column
DX063474	Thermo Scientific™ 063474	10 μm	9 mm	250 mm	Semi-Preparative Column
DXSP5512	Thermo Scientific™ 088767	10 μm	4 mm	250 mm	Column Set (3 Columns, 1 Lot)
DXSP5829	Thermo Scientific™ 088778	10 μm	4 mm	100 mm	Analytical Column
DXSP6703	Thermo Scientific™ 088779	10 μm	4 mm	150 mm	Analytical Column
DX054994	Thermo Scientific™ 054994	10 μm	4 mm	50 mm	Guard Column
DX063480	Thermo Scientific™ 063480	10 μm	2 mm	50 mm	Guard Column

Description

Use Thermo Scientific™ ProPac™ WCX-10 LC Columns to provide exceptionally high resolution for separations of proteins and their variants. Based on stationary phases composed of 10μm nonporous polymeric beads, ProPac columns resolve isoforms that differ by a single charged residue. A thin, hydrophilic layer grafted to the particle core eliminates unwanted secondary interactions. The cation-exchange surface provides pH-based selectivity control and fast mass transfer for high-efficiency separation and moderate capacity.

Multiple Formats for Greater Flexibility

• ProPac WCX-10 column is a weak cation-exchanger with a carboxylate functional group
• Column sizes range from 2mm I.D., for analytical work, up to 22mm I.D. for semi-prep work

Superior Performance for Protein Analysis

• Ideal for characterization and quality control assessment of MAbs and other proteins
• Well-suited for characterization of related protein variants including deamidation and MAb lysine truncation variants
• Unequaled high-resolution separations
• Unmatched column-to-column and lot-to-lot reproducibility eliminates column variability as a concern in stability and QA/QC testing

Specifications

• Particle Size: 10 μm
• Pore Size: Nonporous
• Stationary Phase: Carboxylate
• Column Type: Ion Exchange

• pH: 2 to 12
• Temperature: 60°C
• Product Line: ProPac
• Phase: Ion Exchange

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