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Invivogen POLY(I:C) (HMW) VACCIGRADE
SDP

Supplier:  Invivogen VACPIC

Encompass

Poly(I:C) is a synthetic double-stranded RNA, that can activate the immune response through two distinct PRRs. Endosomal poly(I:C) activates TLR3 while cytosolic poly(I:C) activates RIG-I/MDA-5. Triggering the TLR3 pathway induces IL-12 and type I IFNs production, while stimulation of MDA-5 enhances the production of type I IFNs. Poly(I:C) promotes Th1 biased immunity through its induction of IL-12 and type I IFNs.

Catalog No. NC0465247


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