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TARGETMOL CHEMICALS INC PIN1 INHIBITOR API-1 5MG

Supplier:  TARGETMOL CHEMICALS INC T16538

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Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 200 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. PIN1 inhibitor API-1 is a specific Pin1 inhibitor (IC50 72.3 nM). PIN1 inhibitor API-1 retains the active conformation of pXPO5 and restores the ability of pXPO5 to transport pre-miRNAs from the nucleus to cytoplasm thus up-regulating the anticancer miRNA biogenesis to suppress both in vitro and in vivo hepatocellular carcinoma development. PIN1 inhibitor API-1 directly and specifically binds to the Pin1 peptidyl-prolyl isomerase domain and effectively inhibits Pin1 cis-trans isomerizing activity. purity: 98%

Catalog No. 50-258-1168


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