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Thermo Scientific™ Pierce™ Traut's Reagent (2-iminothiolane)
2-Iminothiolane-HCl (CAS 4781-83-3); an amine-reactive thiolation reagent to cap protein primary amines with sulfhydryl groups for immediate crosslinking.
Supplier: Thermo Scientific™ 26101
Description
Thermo Scientific™ Pierce Traut's Reagent is 2-iminothiolane, a small thiolation compound that reacts with primary amines (e.g., lysine side chains) to add a small spacer arm (8.1 Ås) terminated by a free sulfhydryl group.
Highlights:
- Reacts with primary amines (lysine epsilon amino groups) at pH 7-9
- Adds a short spacer ending in a sulfhydryl group, ready for use as a target for sulfhydryl-specific crosslinking or labeling
- Amine-containing spacer arm preserves charge of original, modified primary amine
Specifications
| Amine | |
| Sulfhydryl Group | |
| Pierce™ | |
| Powder | |
| DMF, DMSO |
| Storage: Upon receipt store product at 4°C with desiccant. Product shipped at ambient temperature | |
| Conjugating Groups | |
| Short (<10 Å) | |
| 500 mg | |
| Thiophilic Adsorption Kit |
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Product Title
For Research Use Only. Not for use in diagnostic procedures.
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