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Tocris Bioscience™ PHT 427
Dual Akt and PDK1 inhibitor; antitumor
$150.80 - $503.44
Specifications
| Purity | >98% |
|---|---|
| Product Type | PHT 427 |
| Molecular Weight (g/mol) | 409.61 |
| Inhibitors | PHT 427 |
Description
Dual Akt and PDK1 inhibitor; binds the pleckstrin homology (PH) domain of Akt and PDK1 (Ki values are 2.7 and 5.2 μM, respectively). Inhibits Akt phosphorylation and Akt downstream targets; also induces apoptosis in vitro. Displays synergistic antitumor effect when combined with chemotherapeutics in breast cancer mouse models.Specifications
| >98% | |
| PHT 427 | |
| 409.61 | |
| PHT 427 |
For Research Use Only
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