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Phenyl chloroformate, 99%, Thermo Scientific Chemicals
Description
Phenyl chloroformate is used in the synthesis of poly(2-(phenoxycarbonyloxy)ethyl methacrylate) and phenyl-(4-vinylphenyl) carbonate. It acts as a precursor of phenyl mixed anhydrides which are used in peptide coupling reactions. It serves as a dehydrating reagent for the conversion of primary amides to nitriles and an intermediate in the synthesis of pharmaceuticals and carbamates.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Phenyl chloroformate is used in the synthesis of poly(2-(phenoxycarbonyloxy)ethyl methacrylate) and phenyl-(4-vinylphenyl) carbonate. It acts as a precursor of phenyl mixed anhydrides which are used in peptide coupling reactions. It serves as a dehydrating reagent for the conversion of primary amides to nitriles and an intermediate in the synthesis of pharmaceuticals and carbamates.
Solubility
Miscible with N,N-dimethylformamide.
Notes
Store in cool place. Moisture sensitive. Keep the container tightly closed in a dry and well-ventilated place. Incompatible with bases, alcohols and amines. Hydrolyses in water.
Specifications
Melting Point | -38°C |
Density | 1.246 |
Boiling Point | 188°C to 189°C |
Flash Point | 76°C (169°F) |
Refractive Index | 1.511 |
Quantity | 100 g |
UN Number | UN2746 |
Beilstein | 606778 |
Sensitivity | Moisture sensitive |
Solubility Information | Miscible with N,N-dimethylformamide. |
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Safety and Handling
Hazard Category | H227-H302-H314-H317-H330-H335 |
Hazard Statement | GHS H Statement H330-H314-H318-H227-H302-H317 Fatal if inhaled. Causes severe skin burns and eye damage. Causes serious eye damage. Combustible liquid. Harmful if swallowed. May cause an allergic skin reaction. |
Precautionary Statement | P210-P235-P260-P264b-P270-P271-P272-P280-P284-P303+P361+P353-P304+P340-P305+P351+P338-P310-P330-P331-P333+P313-P363-P370+P378q-P501c |
DOTInformation | Transport Hazard Class: 6.1; Packing Group: II; Proper Shipping Name: PHENYL CHLOROFORMATE |
EINECSNumber | 217-547-8 |
RTECSNumber | FG3850000 |
TSCA | Yes |
Recommended Storage | Keep cold; Store under Nitrogen |
RUO – Research Use Only
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