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  7. Thermo Scientific Chemicals Paclitaxel, 99+%

Thermo Scientific Chemicals Paclitaxel, 99+%

Catalog Number AC328420250
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Quantity:
1 mg
5 mg
25 mg
33069-62-4
C47H51NO14
853.92
MFCD00869953
RCINICONZNJXQF-VAZQATRQSA-N
paclitaxel, taxol, taxol a, abraxane, paxene, paxceed, plaxicel, yewtaxan, onxol, ebetaxel
133640187
(1S,2S,4S,7R,9S,10S,12R,15S)-4,12-bis(acetyloxy)-1,9-dihydroxy-15-{[(2R,3S)-2-hydroxy-3-phenyl-3-(phenylformamido)propanoyl]oxy}-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo[11.3.1.0³,¹⁰.0⁴,⁷]heptadec-13-en-2-yl benzoate
CC(=O)O[C@@H]1C2=C(C)[C@H](C[C@@](O)([C@@H](OC(=O)C3=CC=CC=C3)C3[C@@]4(CO[C@@H]4C[C@H](O)[C@@]3(C)C1=O)OC(C)=O)C2(C)C)OC(=O)[C@H](O)[C@@H](NC(=O)C1=CC=CC=C1)C1=CC=CC=C1
33069-62-4
C47H51NO14
853.92
MFCD00869953
RCINICONZNJXQF-VAZQATRQSA-N
paclitaxel, taxol, taxol a, abraxane, paxene, paxceed, plaxicel, yewtaxan, onxol, ebetaxel
133640187
(1S,2S,4S,7R,9S,10S,12R,15S)-4,12-bis(acetyloxy)-1,9-dihydroxy-15-{[(2R,3S)-2-hydroxy-3-phenyl-3-(phenylformamido)propanoyl]oxy}-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo[11.3.1.0³,¹⁰.0⁴,⁷]heptadec-13-en-2-yl benzoate
CC(=O)O[C@@H]1C2=C(C)[C@H](C[C@@](O)([C@@H](OC(=O)C3=CC=CC=C3)C3[C@@]4(CO[C@@H]4C[C@H](O)[C@@]3(C)C1=O)OC(C)=O)C2(C)C)OC(=O)[C@H](O)[C@@H](NC(=O)C1=CC=CC=C1)C1=CC=CC=C1

Description

Paclitaxel, also known as Taxol, CAS # 33069-62-4 is a chemotherapeutic drug that acts through stabilizing microtubule assembly and arresting cell cycle progression.

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description
Paclitaxel is a naturally ocurring compound originally isolated from the tree T. brevifolia
Paclitaxel binds tubulin and stabilizes microtubule formation, preventing disassembly
Paclitaxel is used as a drug to arrest cells at the mitotic checkpoint and block cell cycle progression, thus inducing death of cancer cells
Applications
Paclitaxel can be used in preclinical laboratory research on diseases such as cancer, heart disease, inflammatory disorders, and hepatic fibrosis
Paclitaxel can be used as a tool in cell biology to study mitotic checkpoint arrest conditions and downstream signaling cascades
TRUSTED_SUSTAINABILITY
Melting Point 213.0°C to 216.0°C
Color White
Infrared Spectrum Authentic
Assay Percent Range 99% min. (HPLC)
Quantity 25 mg
Merck Index 15, 7081
Solubility Information Solubility in water: sparingly soluble. Other solubilities: soluble in methanol,dmso,acetonitrile
Formula Weight 853.9
Percent Purity 99+%
Physical Form Powder
Chemical Name or Material Paclitaxel, 99+%
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Safety and Handling

Hazard Category GHS Signal Word: Danger
Hazard Statement GHS H Statement:
Causes serious eye damage.
Suspected of causing cancer.
Precautionary Statement GHS P Statement:
Wear eye protection/face protection.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
Immediately call a POISON CENTER or doctor/physician.
Use personal protective equipment as required.

WARNING: The information provided on this web site was developed in compliance with European Union (EU) regulations and is correct to the best of our knowledge, information and belief at the date of its publication. The information given is designed only as a guide for safe handling and use. It is not to be considered as either a warranty or quality specification.
RTECSNumber DA8340700
SDS

RUO – Research Use Only

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