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Omeprazole, Tocris Bioscience™

Catalog Number 258350
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Quantity:
50 mg
This item is not returnable. View return policy
73590-58-6
C17H19N3O3S
345.417
SUBDBMMJDZJVOS-UHFFFAOYSA-N
omeprazole, losec, prilosec, antra, esomeprazole, omeprazon, audazol, omapren, omepral, parizac
4594
CHEBI:77260
6-methoxy-2-[(4-methoxy-3,5-dimethylpyridin-2-yl)methylsulfinyl]-1H-benzimidazole
CC1=CN=C(C(=C1OC)C)CS(=O)C2=NC3=C(N2)C=C(C=C3)OC
This item is not returnable. View return policy
73590-58-6
C17H19N3O3S
345.417
SUBDBMMJDZJVOS-UHFFFAOYSA-N
omeprazole, losec, prilosec, antra, esomeprazole, omeprazon, audazol, omapren, omepral, parizac
4594
CHEBI:77260
6-methoxy-2-[(4-methoxy-3,5-dimethylpyridin-2-yl)methylsulfinyl]-1H-benzimidazole
CC1=CN=C(C(=C1OC)C)CS(=O)C2=NC3=C(N2)C=C(C=C3)OC

Description

H+,K+-ATPase inhibitor

H+,K+-ATPase inhibitor (IC50 = 5.8 μM) that displays antisecretory and antiulcer activity. Inhibits gastric acid secretion (IC50 = 0.16 μM for histamine-induced acid formation) and reduces gastric lesion formation induced by a variety of ulcerative stimuli. Antibacteral against Helicobacter pylori in vitro. Also inhibits CYP2C19, CYP2C9 and CYP3A (Ki values are 3.1, 40.1 and 84.4 μM respectively) and blocks swelling-dependent chloride channels (ICIswell). Enhances anti-SARS-CoV-2 acitvity of Remdesivir and Aprotinin (Cat. No. 4139).
Quantity 50 mg
Formula Weight 345.42
Percent Purity >99%
Chemical Name or Material Omeprazole

Safety and Handling

Recommended Storage Desiccate at +4°C
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