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NCL 00017509, Tocris Bioscience™
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Quantity:
1 mg
Description
NCL 00017509 is a potent and reversible NIMA related kinase 2 (Nek2) inhibitor (IC50 = 56 nM). Induces increased mitotic abnormalities and mitotic delay. Cell permeable and active in vivo. In mice bearing pancreatic tumors, NCL 00017509 decreases PD-L1 expression and induces an anticancer immune response.
Specifications
Linear Formula | C15H12N6O |
Quantity | 1 mg |
Solubility Information | Soluble to 100mM in DMSO |
Formula Weight | 292.3 |
Physical Form | Solid |
Chemical Name or Material | 3-[(6-Ethynyl-9H-purin-2-yl)amino]benzeneacetamide |
Grade | >97% |
Safety and Handling
Recommended Storage | Store at −20°C |
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