N-(9-Fluorenylmethoxycarbonyloxy)succinimide, 98%, Thermo Scientific Chemicals

Description

N-(9-Fluorenylmethoxycarbonyloxy)succinimide is the most efficient reagent for the selective preparation of N-(9-fluorenylmethoxycarbonyl) derivatives of hydroxy-amino acids. Dipeptide formation is lower than with the chloroformate, Fmoc-Cl. It is also employed in the synthesis of glycopeptides.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
N-(9-Fluorenylmethoxycarbonyloxy)succinimide is the most efficient reagent for the selective preparation of N-(9-fluorenylmethoxycarbonyl) derivatives of hydroxy-amino acids. Dipeptide formation is lower than with the chloroformate, Fmoc-Cl. It is also employed in the synthesis of glycopeptides.

Solubility
Soluble in dimethyl sulfoxide and dimethyl formamide.

Notes
Store in a cool place. Moisture sensitive. Keep the container tightly closed in a dry and well-ventilated place. Incompatible with strong acids.

Specifications

Chemical Identifiers

• CAS: 82911-69-1
• Molecular Formula: C19H15NO5
• Molecular Weight (g/mol): 337.331
• MDL Number: MFCD00010733
• InChI Key: WMSUFWLPZLCIHP-UHFFFAOYSA-N
• Synonym: fmoc-osu, n-9-fluorenylmethoxycarbonyloxy succinimide, fmoc-onsu, 9-fluorenylmethyl succinimidyl carbonate, fmoc n-hydroxysuccinimide ester, 9h-fluoren-9-yl methyl 2,5-dioxopyrrolidin-1-yl carbonate, 9-fluorenylmethyl n-succinimidyl carbonate, 9-fluorenylmethylsuccinimidyl carbonate, 9-fluorenylmethoxycarbonyl-n-hydroxysuccinimide
• PubChem CID: 134122
• IUPAC Name: (2,5-dioxopyrrolidin-1-yl) 9H-fluoren-9-ylmethyl carbonate
• SMILES: C1CC(=O)N(C1=O)OC(=O)OCC2C3=CC=CC=C3C4=CC=CC=C24

• Melting Point: 150°C to 153°C
• Quantity: 5 g
• UN Number: UN3077
• Beilstein: 3569540
• Sensitivity: Moisture sensitive
• Solubility Information: Soluble in dimethyl sulfoxide and dimethyl formamide.
• Formula Weight: 337.34
• Percent Purity: 98%
• Chemical Name or Material: N-(9-Fluorenylmethoxycarbonyloxy)succinimide

Safety and Handling

Hazard Category	H302-H317
Hazard Statement	GHS H Statement H301-H317 Toxic if swallowed. May cause an allergic skin reaction.
Precautionary Statement	P261-P264b-P270-P272-P280g-P301+P312-P302+P352-P330-P333+P313-P363-P501c
DOTInformation	Transport Hazard Class: 9; Packing Group: III; Proper Shipping Name: ENVIRONMENTALLY HAZARDOUS SUBSTANCES, SOLID, N.O.S.
EINECSNumber	433-520-5
TSCA	No
Recommended Storage	Keep cold

SDS

RUO – Research Use Only