Hooke Laboratories Inc Hooke Kits™ for EAE Induction in C57BL/6 Mice
Supplier: Hooke Laboratories Inc EK2110
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Hooke Kits™ for EAE Induction in C57BL/6 Mice. Emulsion supplied in pre-filled syringes, ready to use. Consistently induces EAE in female C57BL/6 mice EAE will develop in 90-100% of mice. Disease onset is 9 to 14 days after immunization. Mean maximum score will be 3.0 to 3.5. Each lot is tested and individually adjusted to ensure consistent disease induction. On Day 0, MOG35-55/CFA or MOG1-125/CFA emulsion and pertussis toxin are injected. On Day 1, a second dose of pertussis toxin is injected.roperly prepared emulsions are critical for reliable induction of many autoimmune disease models. Our emulsions are carefully made and pre-filled into syringes, ready to use, to reduce time needed to set up experiments.Lot-to-lot reagent variations can cause dramatic changes in severity of induced autoimmune disease.
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