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Enzo Life Sciences Matrix Metalloproteinase-2 (MMP-2) fluorometric drug discovery kit (1x96wells)
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Supplier:  Enzo Life Sciences BMLAK4090001

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A QUANTIZYME Assay System. The MMP-2 Fluorometric (also known as fluorimetric) Drug Discovery Kit is a complete assay system designed to screen inhibitors of matrix metalloproteinase-2 (MMP-2, gelatinase A) using a quenched fluorogenic peptide: OMNIMMP fluorogenic substrate Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH. Mca fluorescence is quenched by the Dpa group until cleavage by MMPs at the Gly-Leu bond separates the two moieties. The assays are performed in a convenient 96-well microplate format. The kit is useful to screen inhibitors of MMP-2, a potential therapeutic target. Included are active enzyme, assay buffer, a prototypic control inhibitor (NNGH3), and a detailed instruction booklet. Alternative Name: Gelatinase A, 72 kDa Type IV collagenase. Applications: Fluorescent detection, HTS, Activity assay. Contents: MMP-2 enzyme (human) (recombinant), substrate, calibration standard, inhibitor, assay buffer, 96-well white microplate.

Catalog No. NC1464880


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