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Tocris Bioscience™ MM 102
WDR5/MLL interaction inhibitor
Supplier: Tocris Bioscience™ 5307/10
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Description
MM 102 is a potent WDR5/MLL interaction inhibitor (IC50 = 2.4 nM). Inhibits MLL1 methyltransferase activity and MLL-1-induced HoxA9 and Meis-1 gene expression in leukemia cells expressing the MLL1-AF9 fusion gene. Also inhibits cell growth and induces apoptosis in leukemia cells harbouring MLL1 fusion proteins.Specifications
>98% | |
MM 102 | |
MM 102 |
1883545-52-5 | |
783.83 | |
10 mg |
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