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(+)-MK 801 maleate, Tocris Bioscience™
Description
(+)-MK 801 maleate is a high affinity (Ki = 37.2 nM), selective and non-competitive NMDA receptor antagonist. (+)-MK 801 maleate acts by binding to a site located within the NMDA associated ion channel and thus prevents Ca2+ flux. It is an effective anti-ischemic agent in several animal models. (+)-MK 801 maleate increases motor activity in rat models. (+)-MK 801 maleate inhibits proliferation and increases apoptosis in hippocampal neural stem cells (NSCs). (+)-MK 801 maleate induces schizophrenia-like symptoms in rodents.
(-)-enantiomer also available.
Specifications
Quantity | 50 mg |
Formula Weight | 337.37 |
Percent Purity | >99% |
Chemical Name or Material | (+)-MK 801 maleate |
Safety and Handling
Recommended Storage | Store at Room Temperature |
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