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Mirtazapine, Tocris Bioscience™

Catalog No. 201850
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Potent 5-HT2 antagonist; also 5-HT3, H1 and α2 antagonist; antidepressant

Mirtazapine is an antidepressant agent; potent 5-HT2, 5-HT3 and histamine H1 receptor antagonist and moderately potent α2-adrenoceptor antagonist (pKi values are 8.05, ∼ 8.1, 9.3 and 6.95 respectively). Enhances noradrenaline (NA) release in rat brain via inhibition of α2-adrenergic autoreceptors and displays only weak affinity for monoamine transporters (pKi values are 5.6, < 5 and < 5.1 for inhibition of NA, dopamine and 5-HT uptake respectively). Increases hippocampal NA and 5-HT levels in rats following systemic administration in vivo.

Chemical Identifiers

CAS 85650-52-8
Molecular Formula C17H19N3
Molecular Weight (g/mol) 265.36
InChI Key RONZAEMNMFQXRA-UHFFFAOYSA-N
Synonym mirtazapine, remeron, mepirzepine, remergil, zispin, remergon, rexer, 6-azamianserin, remeron soltab, mepirzapin
PubChem CID 4205
ChEBI CHEBI:6950
SMILES CN1CCN2C(C1)C3=CC=CC=C3CC4=C2N=CC=C4

Specifications

Quantity 50 mg
Formula Weight 265.36
Percent Purity >99%
Chemical Name or Material Mirtazapine

Safety and Handling

Recommended Storage Store at Room Temperature
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