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Thermo Scientific™ Micrococcal Nuclease (300 U/μL)

Digest single-stranded and double-stranded DNA and RNA with Thermo Scientific™ Micrococcal Nuclease (S7 Nuclease), an endo-exonuclease.

Supplier:  Thermo Scientific™ EN0181

Catalog No. FEREN0181



Description

Description

Micrococcal Nuclease (S7 Nuclease) is a relatively nonspecific endo-exonuclease that digests single-stranded and double-stranded nucleic acids, but is more active on single-stranded substrates. Cleavage of DNA or RNA occurs preferentially at AT or AU-rich regions, yielding mononucleotides and oligonucleotides with terminal 3'-phosphates. The enzyme's activity is strictly dependent on Ca2+.

Applications

  • Hydrolysis of nucleic acids in crude cell-free extracts
  • Sequencing of RNA
  • Studies of chromatin structure
  • A model for protein folding and for structure-function studies
TRUSTED_SUSTAINABILITY
Specifications

Specifications

300 U/μL
Nuclease
8000 U
Micrococcal Nuclease
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For Research Use Only. Not for use in diagnostic procedures.