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LY 333531 hydrochloride, Tocris Bioscience™

Catalog Number 47381
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Quantity:
1 mg
This item is not returnable. View return policy
169939-93-9
C28H29ClN4O3
505.015
NYQIEYDJYFVLPO-FERBBOLQSA-N
ruboxistaurin hydrochloride, ly 333531 hydrochloride, ly-333531 hydrochloride, unii-6496v4oczn, ly333531 hydrochloride, ruboxistaurin-d6 hydrochloride, ly-333,531 . hydrochloride, 9s-9-dimethylamino methyl-6,7,10,11-tetrahydro-9h,18h-5,21:12,17-di metheno dibenzo e,k pyrrolo 3,4-h 1,4,13 oxadiazacyclohexadecine-18,20 19h-dione hydrochloride
9870785
CN(C)CC1CCN2C=C(C3=CC=CC=C32)C4=C(C5=CN(CCO1)C6=CC=CC=C65)C(=O)NC4=O.Cl
This item is not returnable. View return policy
169939-93-9
C28H29ClN4O3
505.015
NYQIEYDJYFVLPO-FERBBOLQSA-N
ruboxistaurin hydrochloride, ly 333531 hydrochloride, ly-333531 hydrochloride, unii-6496v4oczn, ly333531 hydrochloride, ruboxistaurin-d6 hydrochloride, ly-333,531 . hydrochloride, 9s-9-dimethylamino methyl-6,7,10,11-tetrahydro-9h,18h-5,21:12,17-di metheno dibenzo e,k pyrrolo 3,4-h 1,4,13 oxadiazacyclohexadecine-18,20 19h-dione hydrochloride
9870785
CN(C)CC1CCN2C=C(C3=CC=CC=C32)C4=C(C5=CN(CCO1)C6=CC=CC=C65)C(=O)NC4=O.Cl

Description

Protein kinase C inhibitor; selective for β isozymes

Isozyme-selective inhibitor of protein kinase C (PKC); competitively and reversibly inhibits PKCβI and PKCβII (IC50 values are 4.7 and 5.9 nM respectively). Selective for PKCβ over other PKC isozymes (IC50 values are 0.052, 0.25, 0.30, 0.36, 0.60 and >100 μM for PKCη, -δ, -γ, -α, -ε and -ζ respectively). Exhibits selectivity for PKC over other ATP-dependent kinases, including protein kinase A, casein kinase and src).
Quantity 1 mg
Formula Weight 505.01
Percent Purity >98%
Chemical Name or Material LY 333531 hydrochloride

Safety and Handling

Recommended Storage Store at -20°C
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