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L-(+)-Valinol, 97%, Thermo Scientific Chemicals
Description
L-(+)-Valinol reacts with aldehydes and nitriles to form imines and oxazolines, respectively, for asymmetric synthesis. It is also used for preparation of 4-isopropyloxazolidinones, employed in stereocontrolled aldol and alkylation reactions, synthesis of chiral 2-thiazolidinethiones for aldol reactions, asymmetric alkylation of condensation product with keto acids, asymmetric reactions of its amidines and imines and oxidation of N-protected derivative to the aldehyde.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
L-(+)-Valinol reacts with aldehydes and nitriles to form imines and oxazolines, respectively, for asymmetric synthesis. It is also used for preparation of 4-isopropyloxazolidinones, employed in stereocontrolled aldol and alkylation reactions, synthesis of chiral 2-thiazolidinethiones for aldol reactions, asymmetric alkylation of condensation product with keto acids, asymmetric reactions of its amidines and imines and oxidation of N-protected derivative to the aldehyde.
Solubility
Soluble in water.
Notes
Keep container tightly sealed. Store in cool, dry conditions in well sealed containers. Incompatible with oxidizing agents. It is sensitive to air. Store under dry inert gas.
Specifications
Refractive Index | 1.4548 |
Density | 0.926 |
Boiling Point | 80°C to 81°C (8mmHg) |
Melting Point | 30°C to 35°C |
Quantity | 25 g |
Flash Point | 78°C (172°F) |
Optical Rotation | +17° (c=10 in Ethanol) |
Sensitivity | Air sensitive |
Beilstein | 1719137 |
Solubility Information | Soluble in water. |
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Safety and Handling
GHS H Statement
H315-H319
Causes skin irritation.
Causes serious eye irritation.
P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P362-P501c
H315-H319-H335
EINECSNumber : 217-975-5
TSCA : No
Recommended Storage : Keep cold
RUO – Research Use Only