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Tocris Bioscience™ KYL
EphA4 kinase inhibitor; neuroprotective
Supplier: Tocris Bioscience™ 5290/1
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Description
KYL is an EphA4 receptor tyrosine kinase inhibitor (Kd = 0.8 μM); inhibits EphA4-EphrinA5 interactions (IC50 = 6.34 μM). Prevents AβO induced synaptic damage, dendritic spine loss and prevents the blocking of LTP in hippocampal CA3-CA1 transmissions. Exhibits a long half life in cell culture media (8 and 12 hours in PC3 and C2C12 media respectively). Neuroprotective.Specifications
KYL | |
KYL | |
Lys-Tyr-Leu-Pro-Tyr-Trp-Pro-Val-Leu-Ser-Ser-Leu |
1465.75 | |
1 mg |
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