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Ki 20227, Tocris Bioscience™
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Quantity:
10 mg
50 mg
Description
Inhibitor of c-Fms tyrosine kinase (M-CSFR, CSF1R) (IC50 values are 2, 12, 217 and 451 nM for c-Fms, VEGFR-2, PDGFRβ and c-Kit respectively). Does not inhibit Flt3, EGFR or c-Src. Suppresses osteoclast differentiation and osteolysis in a rat bone metastasis model.
Specifications
Quantity | 50 mg |
Formula Weight | 480.54 |
Percent Purity | >97% |
Chemical Name or Material | Ki 20227 |
Safety and Handling
Recommended Storage | Store at +4°C |
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