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Kaempferol, 98+%, Thermo Scientific™

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Quantity:
50mg
520-18-3
C15H10O6
286.24
MFCD00016938
IYRMWMYZSQPJKC-UHFFFAOYSA-N
kaempferol, kaempherol, kempferol, populnetin, rhamnolutein, robigenin, trifolitin, pelargidenolon, rhamnolutin, swartziol
5280863
CHEBI:28499
3,5,7-trihydroxy-2-(4-hydroxyphenyl)chromen-4-one
OC1=CC=C(C=C1)C1=C(O)C(=O)C2=C(O)C=C(O)C=C2O1
520-18-3
C15H10O6
286.24
MFCD00016938
IYRMWMYZSQPJKC-UHFFFAOYSA-N
kaempferol, kaempherol, kempferol, populnetin, rhamnolutein, robigenin, trifolitin, pelargidenolon, rhamnolutin, swartziol
5280863
CHEBI:28499
3,5,7-trihydroxy-2-(4-hydroxyphenyl)chromen-4-one
OC1=CC=C(C=C1)C1=C(O)C(=O)C2=C(O)C=C(O)C=C2O1

Kaempferol, is used as an inhibitor of Fatty Acid Synthase, Cox-1 activity, and Topo I. It also Induces caspase-9-mediated apoptosis in a variety of cancer cell lines via downregulation of polo-like kinase 1 (PLK1) expression. Exhibits antioxidant activity and attenuates osteoclastic bone reabsorption in vitro. Also blocks EGF-induced histone H3Ser10 phosphorylation in mouse epidermal JB6 C141 cells.

This Thermo Scientific brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific.

Applications
Kaempferol, is used as an inhibitor of Fatty Acid Synthase, Cox-1 activity, and Topo I. It also Induces caspase-9-mediated apoptosis in a variety of cancer cell lines via downregulation of polo-like kinase 1 (PLK1) expression. Exhibits antioxidant activity and attenuates osteoclastic bone reabsorption in vitro. Also blocks EGF-induced histone H3Ser10 phosphorylation in mouse epidermal JB6 C141 cells.

Solubility
Soluble in DMSO or ethanol to 100mM

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Light sensitive. Keep away fom strong oxidizing agents.
Color Yellow
Melting Point 276°C to 278°C
Beilstein 304401
Merck Index 14,5274
Quantity 50mg
Solubility Information Soluble in DMSO or ethanol to 100mM
Formula Weight 286.24
Physical Form Powder
Percent Purity ≥98%
Chemical Name or Material Kaempferol

GHS H Statement
H315-H319-H335
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.

P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P362-P501c

H315-H319-H335

EINECSNumber : 208-287-6

RTECSNumber : LK9275200

TSCA : No

Recommended Storage : Store at -20°C

RUO – Research Use Only