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Indirubin-3'-oxime, Tocris Bioscience™
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Quantity:
10 mg
50 mg
Description
Inhibitor of GSK-3β (IC50 = 190 nM) and cyclin dependent kinases (cdks; IC50 values are 0.05, 0.18 and 0.25-0.5 βM for cdk9, cdk1 and cdk2, respectively). Also reported to inhibit AMPK, LCK and SGK. Inhibits cdk5- and GSK-3β-mediated tau phosphorylation. Induces cell cycle arrest and inhibits cell proliferation.
Specifications
Quantity | 50 mg |
Formula Weight | 277.28 |
Percent Purity | >99% |
Chemical Name or Material | Indirubin-3'-oxime |
Safety and Handling
Recommended Storage | Store at Room Temperature |
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