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Tocris Bioscience™ INCA-6
Inhibitor of calcineurin-substrate association
Supplier: Tocris Bioscience™ 2162/50
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Description
INCA-6 is an inhibitor of interaction between calcineurin and its substrate nuclear factor of activated T cells (NFAT); blocks at the substrate recognition site but not at the catalytic site (Kd = 0.8 mM). Inhibits NFAT dephosphorylation and nuclear import. Also prevents induction of cytokine mRNAs that are downstream targets of NFAT.Specifications
>99% | |
INCA-6 | |
INCA-6 |
50 mg | |
284.31 |
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