Thermo Scientific™ ImmunoCAP™ Tree Pollen Allergens

Measure specifc IgE antibodies using ImmunoCAP™ allergens, an essential tool to aid in the diagnosis of allergic conditions.

Catalog Number	Mfr. No.	Common Name	Scientific Name	Code	Quantity
14-410-201P	Thermo Scientific™ 14410201	Common silver birch	Betula verrucosa	t3	16 Tests
14-411-801P	Thermo Scientific™ 14411801	Japanese cedar	Cryptomeria japonica	t17	16 Tests
14-414-901P	Thermo Scientific™ 14414901	Oak	Quercus alba	t7	16 Tests
14-414-701P	Thermo Scientific™ 14414701	Hazel	Corylus avellana	t4	16 Tests
14-414-801P	Thermo Scientific™ 14414801	American beech	Fagus grandifolia	t5	16 Tests
14-414-601P	Thermo Scientific™ 14414601	Grey alder	Alnus incana	t2	16 Tests
14-415-001P	Thermo Scientific™ 14415001	Olive	Olea europaea	t9	16 Tests
14-415-101P	Thermo Scientific™ 14415101	Willow	Salix caprea	t12	16 Tests
14-416-101P	Thermo Scientific™ 14416101	Box-elder	Acer negundo	t1	16 Tests
14-422-501P	Thermo Scientific™ 14422501	Mountain juniper	Juniperus sabinoides	t6	16 Tests
14-422-601P	Thermo Scientific™ 14422601	Elm	Ulmus americana	t8	16 Tests
14-422-901P	Thermo Scientific™ 14422901	Cottonwood	Populus deltoides	t14	16 Tests
14-422-701P	Thermo Scientific™ 14422701	Walnut	Juglans californica	t10	16 Tests
14-423-001P	Thermo Scientific™ 14423001	White ash	Fraxinus americana	t15	16 Tests
14-423-201P	Thermo Scientific™ 14423201	Eucalyptus, Gum-tree	Eucalyptus spp.	t18	16 Tests
14-423-301P	Thermo Scientific™ 14423301	Acacia	Acacia longifolia	t19	16 Tests
14-423-101P	Thermo Scientific™ 14423101	White pine	Pinus strobus	t16	16 Tests
14-422-801P	Thermo Scientific™ 14422801	Maple leaf sycamore, London plane	Platanus acerifolia	t11	16 Tests
14-423-401P	Thermo Scientific™ 14423401	Mesquite	Prosopis juliflora	t20	16 Tests
14-423-501P	Thermo Scientific™ 14423501	Melaleuca, Cajeput-tree	Melaleuca leucadendron	t21	16 Tests
14-423-601P	Thermo Scientific™ 14423601	Pecan, Hickory	Carya pecan	t22	16 Tests
14-423-701P	Thermo Scientific™ 14423701	Italian/Mediterranean/Funeral cypress	Cupressus sempervirens	t23	16 Tests
14-432-501P	Thermo Scientific™ 14432501	Mulberry	Morus alba	t70	10 Tests
14-437-301P	Thermo Scientific™ 14437301	Queen palm	Arecastrum romanzoffianum	t72	10 Tests
14-437-401P	Thermo Scientific™ 14437401	Australian pine	Casuarina equisetifolia	t73	10 Tests
14-482-301P	Thermo Scientific™ 14482301	Linden	Tilia cordata	t208	10 Tests
14-483-401P	Thermo Scientific™ 14483401	Privet	Ligustrum vulgare	t210	10 Tests
14-494-210P	Thermo Scientific™ 14494210	White hickory	Carya tomentosa (syn. C. alba)	Rt41	10 Tests
14-494-110P	Thermo Scientific™ 14494110	Bald cypress	Taxodium distichum	Rt37	10 Tests
14-494-310P	Thermo Scientific™ 14494310	Hackberry	Celtis occidentalis	Rt44	10 Tests
14-494-410P	Thermo Scientific™ 14494410	Cedar elm	Ulmus crassifolia	Rt45	10 Tests
14-494-610P	Thermo Scientific™ 14494610	Scotch broom	Cytisus scoparius	Rt55	10 Tests
14-494-710P	Thermo Scientific™ 14494710	Bayberry	Myrica cerifera	Rt56	10 Tests
14-494-810P	Thermo Scientific™ 14494810	Red cedar	Juniperus virginiana	Rt57	10 Tests
14-494-910P	Thermo Scientific™ 14494910	Red mulberry	Morus rubra	Rt71	10 Tests
14-500-210P	Thermo Scientific™ 14500210	Elder	Sambucus nigra	Rt205	10 Tests
14-500-510P	Thermo Scientific™ 14500510	Spruce	Picea excelsa	Rt201	10 Tests
14-514-010P	Thermo Scientific™ 14514010	Chestnut	Castanea sativa	Rt206	10 Tests
14-514-810P	Thermo Scientific™ 14514810	Horn beam	Carpinus betulus	Rt209	10 Tests
14-515-510P	Thermo Scientific™ 14515510	Sweet gum	Liquidambar styraciflua	Rt211	10 Tests
14-516-710P	Thermo Scientific™ 14516710	Peppertree	Schinus molle	Rt217	10 Tests
14-518-501P	Thermo Scientific™ 14518501	Cedar	Libocedrus decurrens	t212	10 Tests
14-520-810P	Thermo Scientific™ 14520810	Pine	Pinus radiata	Rt213	10 Tests
14-521-810P	Thermo Scientific™ 14521810	Date	Phoenix canariensis	Rt214	10 Tests
14-525-210P	Thermo Scientific™ 14525210	Virginia live oak	Quercus virginiana	Rt218	10 Tests
14-530-901P	Thermo Scientific™ 14530901	Cypress	Cupressus arizonica	t222	10 Tests
14-514-610P	Thermo Scientific™ 14514610	Douglas fir	Pseudotsuga taxifolia	Rt207	10 Tests

Description

Quantify specific IgE antibodies with ImmunoCAP™ Tree Pollen Allergens, essential tools to aid in the diagnosis of allergic conditions. IgE antibodies appear in human serum and plasma as a result of sensitization to a specific allergen. Measurement of circulating IgE antibodies provides an objective assessment of sensitization to an allergen. In general, low IgE antibody levels indicate a low probability of allergic disease, whereas high antibody levels to an allergen show a higher correlation with an allergic disease.

ImmunoCAP Specific IgE offers the laboratory:

• Truly quantitative measuring range from 0.1 to 100 kUA/L
• Intra-assay CV (%) comparable to routine clinical chemistry immunoassays
• Excellent consistency over time, and between countries, systems, labs and persons

Expected test values
ImmunoCAP Specific IgE detects IgE antibodies in the range 0.1 to 100 kUA /l, where A represents allergen-specific antibodies. The result is reported quantitatively. In clinical practice, 0.35 kUA /l has commonly been used as a cut-off. A large number of studies have been performed to evaluate the clinical performance of ImmunoCAP Specific IgE tests in allergy diagnosis. Clinical performance is expressed as sensitivity, ranging from 84 to 95%, and specificity, ranging from 85 to 94%. Sensitivity and specificity were reported from multi-center studies including several hundred patients tested for a range of different allergens.

• Specimen collection and preparation
• Use serum and plasma (EDTA or heparin) samples from venous or capillary blood
• Collect blood samples using standard procedures
• Keep specimens at room temperature (RT) for shipping purposes only
• Store at 2–8°C up to one week, otherwise store at –20°C
• Avoid repeated freezing and thawing

Note: Blood samples for testing ImmunoCAP drugs and venom should be collected during or close to the event, preferably not later than 6 months after exposure. If the test result is negative and an IgE-mediated reaction is still strongly suspected, it is advisable to draw a new sample and repeat the test at 5 to 6 weeks.

The presence of specific IgE antibodies is useful to identify the allergens that elicit symptoms and signs of allergy in patients with respiratory allergic diseases including asthma, food allergy, and anaphylactic sensitivity.

Knowing IgE antibody levels provides guidance to clinicians to:

• Identify offending allergens
• Tailor advice to individual patients
• Indicate development of tolerance (food allergy, specific immunotherapy)
• Inform optimized individual medical treatment plans
• Refer to specialists appropriately
• Evaluate whether or not specific immunotherapy is an option

Specific IgE testing also aids in the identification of patients at risk of:

• The allergy march – a progression of skin symptoms to respiratory symptoms
• Severe symptoms including asthma exacerbations – a progression of mild symptoms to severe symptoms
• Progression of recurrent symptoms to persistent symptoms

As in all diagnostic testing, a definitive clinical diagnosis should be made by the clinician after evaluation of all clinical and laboratory findings.

Specifications

• Code Type: Tree