Thermo Scientific™ ImmunoCAP™ Fruit and Vegetable Allergens

Measure specifc IgE antibodies using ImmunoCAP™ allergens, an essential tool to aid in the diagnosis of allergic conditions.

Catalog Number	Mfr. No.	Common Name	Scientific Name	Code	Quantity
14-412-901P	Thermo Scientific™ 14412901	Orange	Citrus sinensis	f33	16 Tests
14-418-201P	Thermo Scientific™ 14418201	Tomato	Lycopersicon lycopersicum	f25	16 Tests
14-421-001P	Thermo Scientific™ 14421001	Carrot	Daucus carota	f31	16 Tests
14-421-101P	Thermo Scientific™ 14421101	Potato	Solanum tuberosum	f35	16 Tests
14-421-601P	Thermo Scientific™ 14421601	Strawberry	Fragaria vesca	f44	16 Tests
14-421-901P	Thermo Scientific™ 14421901	Onion	Allium cepa	f48	16 Tests
14-421-801P	Thermo Scientific™ 14421801	Garlic	Allium sativum	f47	16 Tests
14-422-001P	Thermo Scientific™ 14422001	Apple	Malus x domestica	f49	16 Tests
14-429-601P	Thermo Scientific™ 14429601	Celery	Apium graveolens	f85	10 Tests
14-429-501P	Thermo Scientific™ 14429501	Kiwi	Actinidia deliciosa	f84	10 Tests
14-429-801P	Thermo Scientific™ 14429801	Melon	Cucumis melo spp.	f87	10 Tests
14-433-401P	Thermo Scientific™ 14433401	Banana	Musa spp.	f92	10 Tests
14-433-601P	Thermo Scientific™ 14433601	Pear	Pyrus communis	f94	10 Tests
14-433-101P	Thermo Scientific™ 14433101	Mango	Mangifera indica	f91	10 Tests
14-433-701P	Thermo Scientific™ 14433701	Peach	Prunus persica	f95	10 Tests
14-434-601P	Thermo Scientific™ 14434601	Avocado	Persea americana	f96	10 Tests
14-443-101P	Thermo Scientific™ 14443101	Grapefruit	Citrus paradisi	f209	16 Tests
14-443-201P	Thermo Scientific™ 14443201	Spinach	Spinachia oleracea	f214	16 Tests
14-443-301P	Thermo Scientific™ 14443301	Pumpkin	Cucurbita pepo	f225	16 Tests
14-445-501P	Thermo Scientific™ 14445501	Bamboo shoot	Phyllostachys pubescens	f51	16 Tests
14-445-801P	Thermo Scientific™ 14445801	Sweet potato	Ipomea batatas	f54	16 Tests
14-480-901P	Thermo Scientific™ 14480901	Grape	Vitis vinifera	f259	10 Tests
14-481-001P	Thermo Scientific™ 14481001	Pineapple	Ananas comosus	f210	10 Tests
14-481-101P	Thermo Scientific™ 14481101	Cherry	Prunus avium	f242	10 Tests
14-481-201P	Thermo Scientific™ 14481201	Apricot	Prunus armeniaca	f237	10 Tests
14-481-301P	Thermo Scientific™ 14481301	Lettuce	Lactuca sativa	f215	10 Tests
14-481-401P	Thermo Scientific™ 14481401	Cabbage	Brassica oleracea var. capitata	f216	10 Tests
14-482-901P	Thermo Scientific™ 14482901	Lemon	Citrus limon	f208	10 Tests
14-483-901P	Thermo Scientific™ 14483901	Cucumber	Cucumis sativus	f244	10 Tests
14-484-101P	Thermo Scientific™ 14484101	Broccoli	Brassica oleracea var. italica	f260	10 Tests
14-484-001P	Thermo Scientific™ 14484001	Plum	Prunus domestica	f255	10 Tests
14-504-710P	Thermo Scientific™ 14504710	Aubergine, eggplant	Solanum melongena	Rf262	10 Tests
14-504-610P	Thermo Scientific™ 14504610	Asparagus	Asparagus officinalis	Rf261	10 Tests
14-505-110P	Thermo Scientific™ 14505110	Blackberry	Rubus fruticosus	Rf211	10 Tests
14-505-210P	Thermo Scientific™ 14505210	Blueberry	Vaccinium myrtillis	Rf288	10 Tests
14-506-010P	Thermo Scientific™ 14506010	Cauliflower	Brassica oleracea var. botrytis	Rf291	10 Tests
14-505-410P	Thermo Scientific™ 14505410	Brussel sprouts	Brassica oleracea var. gemmifera	Rf217	10 Tests
14-506-810P	Thermo Scientific™ 14506810	Date	Phoenix dactylifera	Rf289	10 Tests
14-508-910P	Thermo Scientific™ 14508910	Papaya	Carica papaya	Rf293	10 Tests
14-509-110P	Thermo Scientific™ 14509110	Passion fruit	Passiflora edulis	Ff294	10 Tests
14-516-110P	Thermo Scientific™ 14516110	Persimmon	Diospyros kaki	Rf301	10 Tests
14-516-010P	Thermo Scientific™ 14516010	Mandarin	Citrus reticulata	Rf302	10 Tests
14-518-810P	Thermo Scientific™ 14518810	Lime	Citrus aurantifolia	Rf306	10 Tests
14-521-610P	Thermo Scientific™ 14521610	Beetroot	Beta vulgaris	Rf319	10 Tests
14-522-110P	Thermo Scientific™ 14522110	Red currant	Ribes sylvestre	Rf322	10 Tests
14-524-410P	Thermo Scientific™ 14524410	Fig	Ficus carica	Rf328	10 Tests
14-524-510P	Thermo Scientific™ 14524510	Watermelon	Citrullus lanatus	Rf329	10 Tests
14-526-910P	Thermo Scientific™ 14526910	Cranberry	Vaccinium oxycoccus	Rf341	10 Tests
14-527-910P	Thermo Scientific™ 14527910	Olive (black, fresh)	Olea europaea	Rf342	10 Tests
14-528-010P	Thermo Scientific™ 14528010	Raspberry	Rubus idaeus	Rf343	10 Tests
14-521-510P	Thermo Scientific™ 14521510	Jack fruit	Artocarpus heterophyllus	Rf318	10 Tests

Description

Quantify specific IgE antibodies with ImmunoCAP™ Fruit and Vegetable Allergens, essential tools to aid in the diagnosis of allergic conditions. IgE antibodies appear in human serum and plasma as a result of sensitization to a specific allergen. Measurement of circulating IgE antibodies provides an objective assessment of sensitization to an allergen. In general, low IgE antibody levels indicate a low probability of allergic disease, whereas high antibody levels to an allergen show a higher correlation with an allergic disease.

ImmunoCAP Specific IgE offers the laboratory:

• Truly quantitative measuring range from 0.1 to 100 kUA/L
• Intra-assay CV (%) comparable to routine clinical chemistry immunoassays
• Excellent consistency over time, and between countries, systems, labs and persons

Expected test values
ImmunoCAP Specific IgE detects IgE antibodies in the range 0.1 to 100 kUA /l, where A represents allergen-specific antibodies. The result is reported quantitatively. In clinical practice, 0.35 kUA /l has commonly been used as a cut-off. A large number of studies have been performed to evaluate the clinical performance of ImmunoCAP Specific IgE tests in allergy diagnosis. Clinical performance is expressed as sensitivity, ranging from 84 to 95%, and specificity, ranging from 85 to 94%. Sensitivity and specificity were reported from multi-center studies including several hundred patients tested for a range of different allergens.

• Specimen collection and preparation
• Use serum and plasma (EDTA or heparin) samples from venous or capillary blood
• Collect blood samples using standard procedures
• Keep specimens at room temperature (RT) for shipping purposes only
• Store at 2–8°C up to one week, otherwise store at –20°C
• Avoid repeated freezing and thawing

Note: Blood samples for testing ImmunoCAP drugs and venom should be collected during or close to the event, preferably not later than 6 months after exposure. If the test result is negative and an IgE-mediated reaction is still strongly suspected, it is advisable to draw a new sample and repeat the test at 5 to 6 weeks.

The presence of specific IgE antibodies is useful to identify the allergens that elicit symptoms and signs of allergy in patients with respiratory allergic diseases including asthma, food allergy, and anaphylactic sensitivity.

Knowing IgE antibody levels provides guidance to clinicians to:

• Identify offending allergens
• Tailor advice to individual patients
• Indicate development of tolerance (food allergy, specific immunotherapy)
• Inform optimized individual medical treatment plans
• Refer to specialists appropriately
• Evaluate whether or not specific immunotherapy is an option

Specific IgE testing also aids in the identification of patients at risk of:

• The allergy march – a progression of skin symptoms to respiratory symptoms
• Severe symptoms including asthma exacerbations – a progression of mild symptoms to severe symptoms
• Progression of recurrent symptoms to persistent symptoms

As in all diagnostic testing, a definitive clinical diagnosis should be made by the clinician after evaluation of all clinical and laboratory findings.

Specifications

• Code Type: Fruit/Vegetable