Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

Thermo Scientific™ Imject™ cBSA (in PBS)

Prepare hapten-carrier conjugates to generate antibodies using this convenient and highly immunogenic, cationized BSA carrier protein.

Manufacturer:  Thermo Scientific™ 77150

Catalog No. PI77150



Description

Description

Thermo Scientific™ Imject Cationized Bovine Serum Albumin (cBSA) functions as an easy-to-use and highly immunogenic carrier protein for preparing antigens for use in antibody production.

Imject cBSA is prepared by modifying native BSA with excess ethylenediamine, essentially capping all negatively-charged carboxyl groups with positively-charged primary amines. The result is a highly positively-charged protein (pI > 11) that has significantly increased immunogenicity compared to native BSA. In addition, the increased number of primary amines provides for a greater number of antigen molecules to be conjugated with typical crosslinking methods.

Imject cBSA is an excellent choice for immunogen preparation when greater immunogenicity is needed relative to BSA but conditions are not amenable to using keyhole limpet hemocyanin (KLH) or Blue Carrier™ Protein.

Highlights:

  • Convenient – purified bovine serum albumin (BSA) that is cationized and supplied lyophilized in PBS

  • Single polypeptide – modified BSA protein with molecular mass greater than 67,000 daltons

  • Multiple conjugation sites – contains 59 lysine residues, plus numerous other primary amines added by cationization, most of which are capable of reacting with a conjugation reagent to attach antigens

  • Net positive charge – confers solubility in conditions not suitable for the negatively-charged native BSA

  • Immunogenic – significantly greater immunogenicity than native BSA because the positively charged protein is processed differently by the immune-response system

Specifications

Specifications

Imject™
4°C
SDS
Documents

Documents

Product Certifications
Promotions

Promotions

Provide Content Correction

We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Cancel Submit