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  7. Hypoxanthine, 99%, Thermo Scientific Chemicals

Hypoxanthine, 99%, Thermo Scientific Chemicals

Catalog Number AAA1148106
Click to view available options
Quantity:
5 g
25 g
100 g
68-94-0
C5H4N4O
136.11
MFCD00005725
FDGQSTZJBFJUBT-UHFFFAOYSA-N
hypoxanthine, 6-hydroxypurine, 9h-purin-6-ol, sarkin, 6-oxopurine, sarcine, sarkine, 3h-purin-6-ol, 7h-purin-6-ol, purin-6 1h-one
790
CHEBI:17368
3,7-dihydropurin-6-one
O=C1N=CNC2=C1NC=N2
68-94-0
C5H4N4O
136.11
MFCD00005725
FDGQSTZJBFJUBT-UHFFFAOYSA-N
hypoxanthine, 6-hydroxypurine, 9h-purin-6-ol, sarkin, 6-oxopurine, sarcine, sarkine, 3h-purin-6-ol, 7h-purin-6-ol, purin-6 1h-one
790
CHEBI:17368
3,7-dihydropurin-6-one
O=C1N=CNC2=C1NC=N2

Description

Hypoxanthine, is used as a marker for energy perturbation in hypoxia/ ischemia. It has been also used in DNA studies to investigate the destabilizing effect it has on DNA duplexes containing hypoxanthine as a base, in a gas phase versus a liquid phase. Hypoxanthine has also been used in studies along with 8-oxoguanine nucleotides to investigate their interaction with human DNA pol A (DNA polymerase alpha) and DNA polymerase I from Bacillus stearothermophilus. It is also used as a pharmaceutical intermediate.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Hypoxanthine, is used as a marker for energy perturbation in hypoxia/ ischemia. It has been also used in DNA studies to investigate the destabilizing effect it has on DNA duplexes containing hypoxanthine as a base, in a gas phase versus a liquid phase. Hypoxanthine has also been used in studies along with 8-oxoguanine nucleotides to investigate their interaction with human DNA pol å (DNA polymerase alpha) and DNA polymerase I from Bacillus stearothermophilus. It is also used as a pharmaceutical intermediate.

Solubility
It does not mix appreciably with water (1:1400). Small octahedra crystals from water.

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Incompatible to Strong oxidizing agents. Stable under recommended storage conditions. Sterilize by filtration through a 0.22 µm filter.
TRUSTED_SUSTAINABILITY
Melting Point >300°C
Quantity 5 g
Beilstein 5811
Merck Index 14,4869
Solubility Information It does not mix appreciably with water (1:1400). Small octahedra crystals from water.
Formula Weight 136.11
Percent Purity 99%
Chemical Name or Material Hypoxanthine

Safety and Handling

Hazard Category H302-H315-H319-H335
Precautionary Statement P261-P264b-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P312-P330-P332+P313-P362-P501c
EINECSNumber 200-697-3
RTECSNumber UP0791000
TSCA Yes
Recommended Storage Keep cold
SDS

RUO – Research Use Only

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