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Cytiva™ HyClone™ ActiSM™ Cell Culture Media

A chemically defined ADCF cell culture medium optimized for high-yield protein production in CHO cell culture processes.

Supplier:  Cytiva™ SH31040.02

Catalog No. SH3104002

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ActiSM™ cell culture media is a chemically defined animal-derived component-free (ADCF) cultured media optimized for high-yield protein production for bioprocessing. This HyClone™ medium is designed for use with ActiPro™ cell culture media.

  • Chemically defined ADCF formulation optimized for high-yield protein production
  • Does not contain hypoxanthine, thymidine, and glycine (HAT supplement)
  • Recommended for first step when adapting cells cultured in other lean cell culture media

ActiSM™ medium is intended for use in combination with ActiPro™ medium and Cell Boost™ 7a and Cell Boost™ 7b supplements. This HyClone™ medium is part of the ActiPro™ system of media and supplements designed with adaptation and production in mind. ActiSM™ and the ActiPro™ system are suitable for general biomanufacturing with CHO cell lines such as CHO-GS, CHO-K1, CHO-DG44, and CHO-S. Once your process has been adapted for use with the ActiSM™ medium, we recommend utilizing ActiPro™ medium for production.

ActiSM™ cell culture medium is available in both powder and liquid formats. ActiSM™ medium does not contain any growth factors (such as insulin), peptides, hydrolysates, phenol red, or 2-mercaptoethanol, ensuring CHO batch-to-batch consistency. Cell culture media formulations and delivery systems can be customized to your specific process requirements or optimized to maximize process yields. Our cell culture media and development service is available to help you analyze, develop, and optimize your cell culture strategies.



Protein Production
Cell Culture Media
0.2 μm Sterile-filtered
No Glutamine, No Thymidine, No Hypoxanthine, No Glycine
1000 mL
Mammalian Cell Culture
Poloxamer 188
HyClone™ ActiSM™
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ShelfLife : 12 Months



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